“…There are several data (4,5,8,16) which stated that, during the first 7 days, there is a significant increase in the percentage ratio of the Barr corpuscles and that, parallel with this, also the effect of maternal estrogens reflected in the karyopycnotic index disappears. According to the investigations of Diczfalusy et al (3), the amount of estriol excreted with meconium and feces, though consider able in the first postnatal days, decreases to a subminimal level on the fifth day of life.…”