Sex Age Annotated omics Data: Enabling powerful omics studies

Abstract

There is increasing evidence that many molecular processes exhibit differences with age 1
 and sex. Such differences produces also differences in the insurgence and progression of many 2
 complex diseases. For instances, demographic data on insurgence of comorbidities of mellitus 3
 diabetes, on lethality of COVID-19, and on some cancers, shows differences between sex and age 4
 groups. Therefore, the growing interest on such area requires the management of related data as 5
 well as the development of algorithms and tool for the analysis. The availability of omics data 6
 annotated with metadata related to age and sex is mandatory for building pipeline of the analysis. 7
 The number of databases containing data related to age and sex is hencefort growing. We here show 8
 some databases and tools storing such data. Finally, future research direction are highlighte