Sevoflurane versus propofol for electroconvulsive therapy: effects on seizure parameters, anesthesia recovery, and the bispectral index

Pekel, M.; Postaci, Nadide Aysun; Aytaç, İsmail; Karasu, Derya; Keleş, Hüseyin; Şen, Özlem; Dikmen, Bayazıt; Göka, Erol

doi:10.3906/sag-1502-110

Cited by 6 publications

(4 citation statements)

References 22 publications

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“…In this study,17 compared with T0, the whole blood viscosity of the observation group under high, middle and low shear rates decreased significantly at T1, T2 and T3, and were significantly lower than that of the control group. It was concluded that intravenous anesthesia with propofol could effectively reduce the hemorheological parameters, similar to previous studies 18,19…”

Section: Discussionsupporting

confidence: 88%

Influence of propofol intravenous anesthesia on hemorheology, haemodynamics and immune function of colorectal carcinoma patients undergoing radical resection

Han

Geng

2019

Pak J Med Sci

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Objective: To analyze the changes of hemorheology, haemodynamics and immune function of patients during propofol intravenous anesthesia in the radical resection of colorectal carcinoma and its significance. Methods: The study included 112 patients who underwent radical resection of colorectal carcinoma in our hospital between August 2016 and December 2017, and they were divided into an observation group (N=56) and a control group (N=56) using random number table. Patients in the observation group were given propofol intravenous anesthesia, while patients in the control group received inhalation anesthesia of sevoflurane. Hemorheological and haemodynamical indexes were compared and analyzed before anesthesia (T0), 90 min after induction (T1), 150 min after induction (T2) and 30 min after entering post-anesthesia care unit (T3), and the changes of immune function before and after surgery was also observed. Results: The whole blood viscosity under high, medium and low shear rates of the observation group declined significantly compared to that of the control group at T1, T2 and T3 (P<0.05). The heart rate (HR) and systolic pressure (SPB) of the observation group significantly decreased at T2 compared to those at T1 (P<0.05), but recovered to the level observed at T0 at T3. The diastolic blood pressure (DBP) of the two groups at T1, T2 and T3 was not significantly different with that at T0 (P>0.05). The levels of CD45RA+ and CD45RO+ of both groups had a significant decrease at the end of the surgery compared to before anesthesia (P<0.05); the levels of the observation group recovered at the postoperative 72nd h, and the differences with the levels before anesthesia had no statistical significance (P>0.05); the level of CD45RA+ of the control group also recovered at the postoperative 72nd h, but the difference with the level before anesthesia had no statistical significance (P>0.05); the level of CD45RO+ of the control group had a significant decrease, and the difference with the level before anesthesia was statistically significant (P<0.05). The level of CD45RA+/CD45RO+ of the observation group at the end of surgery and the postoperative 72nd h was not significantly different with those before anesthesia (P>0.05). The level of CD45RA+/CD45RO+ of the control group at the postoperative 72nd h showed a significant increase compared to before anesthesia (P<0.05). Conclusion: Propofol intravenous anesthesia has a significant improvement effect on hemorheology before radical resection of colorectal carcinoma and has a small influence on haemodynamics. Moreover it is beneficial to the recovery of immune function. The therapy is worth promotion. doi: https://doi.org/10.12669/pjms.35.3.590 How to cite this:Yu J, Han M, Geng J. Influence of propofol intravenous anesthesia on hemorheology, haemodynamics and immune function of colorectal carcinoma patients undergoing radical resection. Pak J Med Sci. 2019;35(3):---------. doi: https://doi.org/10.12669/pjms.35.3.590 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionsupporting

confidence: 88%

Influence of propofol intravenous anesthesia on hemorheology, haemodynamics and immune function of colorectal carcinoma patients undergoing radical resection

Han

Geng

2019

Pak J Med Sci

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“…ECT is a treatment option for the most severe psychiatric disorders, making it difficult to conduct a randomized controlled trial on the impact of the anesthetic type used during treatment administration ( Fond et al, 2016 ); consequently, we used PS matching in this study. Previous studies on the use of sevoflurane in ECT involved crossover or parallel randomized designs ( Calarge et al, 2003 ; Wajima et al, 2003 ; Hodgson et al, 2004 ; Loughnan et al, 2004 ; Toprak et al, 2005 ; Rasmussen et al, 2006 , 2007 ; Matsubara et al, 2012 ; Begeç et al, 2013 ; Jadeja et al, 2014 ; Ulusoy et al, 2014 ; Erdil et al, 2015a , b , 2017 ; Pekel et al, 2016 ; Aoki et al, 2021 ). To the best of our knowledge, this is the first study to investigate the impact of sevoflurane used during the entire treatment course on the clinical efficacy and seizure adequacy of ECT.…”

Section: Discussionmentioning

confidence: 99%

“…These factors may negatively affect seizure adequacy. Previous studies have investigated the effect of sevoflurane on ECT using a crossover design ( Calarge et al, 2003 ; Wajima et al, 2003 ; Hodgson et al, 2004 ; Loughnan et al, 2004 ; Rasmussen et al, 2005 , 2006 , 2007 ; Toprak et al, 2005 ; Matsubara et al, 2012 ; Begeç et al, 2013 ; Jadeja et al, 2014 ; Ulusoy et al, 2014 ; Erdil et al, 2015a , b , 2017 ; Pekel et al, 2016 ; Aoki et al, 2021 ). However, to the best of our knowledge, no previous study has investigated the effects of sevoflurane used throughout the course of ECT (i.e., when sevoflurane was used in all sessions of the course of ECT).…”

Section: Introductionmentioning

confidence: 99%

Impact of Sevoflurane and Thiopental Used Over the Course of Electroconvulsive Therapy: Propensity Score Matching Analysis

Yatomi

Uchida

Takamiya

et al. 2022

Front. Hum. Neurosci.

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ObjectiveAlthough anesthetics play an important role in electroconvulsive therapy (ECT), the clinical efficacy and seizure adequacy of sevoflurane in the course of ECT remain unclear. The purpose of this study was to examine the clinical efficacy and seizure adequacy of sevoflurane, compared with those of thiopental, in the course of ECT in patients with mood disorders.MethodsWe conducted a retrospective chart review. Patients who underwent a course of ECT and received sevoflurane (n = 26) or thiopental (n = 26) were included. Factors associated with ECT and treatment outcomes were compared between the two groups using propensity score (PS) matching. Between-group differences were examined using an independent t-test for continuous variables and a χ2-test for categorical variables.ResultsPatients who received sevoflurane needed more stimulations (sevoflurane: 13.2 ± 4 times, thiopental: 10.0 ± 2.5 times, df = 51, p = 0.001) and sessions (sevoflurane: 10.0 ± 2.1 times, thiopental: 8.4 ± 2.1 times, df = 51, p = 0.01) and had more inadequate seizures (sevoflurane: 5 ± 3.9 times, thiopental: 2.7 ± 2.7 times, df = 51, p = 0.015). Remission and response rates were similar in both groups.ConclusionThe present findings indicate that sevoflurane should be used with caution in ECT and only when the clinical rationale is clear.

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“…Twelve studies were identified concerning the use of the BIS system during anaesthesia for electroconvulsive therapy [47][48][49][50][51][52][53][54][55][56][57][58]; all observational studies with varied hypotheses. The majority intended to assess correlation between depth of anaesthesia and the duration of seizure, as a proxy for efficacy of the procedure.…”

Section: Electro-convulsive Therapy Studiesmentioning

confidence: 99%

Processed EEG from depth of anaesthesia monitors and seizures: A scoping review

Gimson¹,

Smith²

2021

Seizure

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Sevoflurane versus propofol for electroconvulsive therapy: effects on seizure parameters, anesthesia recovery, and the bispectral index

Abstract: Sevoflurane (5%) may be an effective alternative to propofol for induction of anesthesia for ECT.

Cited by 6 publications

References 22 publications

Influence of propofol intravenous anesthesia on hemorheology, haemodynamics and immune function of colorectal carcinoma patients undergoing radical resection

Influence of propofol intravenous anesthesia on hemorheology, haemodynamics and immune function of colorectal carcinoma patients undergoing radical resection

Impact of Sevoflurane and Thiopental Used Over the Course of Electroconvulsive Therapy: Propensity Score Matching Analysis

Processed EEG from depth of anaesthesia monitors and seizures: A scoping review

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