Severity of sarcopenia is associated with postural balance and risk of falls in community-dwelling older women

Gadelha, André Bonadias; Neri, Silvia Gonçalves Ricci; Oliveira, Ricardo Jacó de; Bottaro, Martim; David, Ana Cristina de; Vainshelboim, Baruch; Lima, Ricardo Moreno

doi:10.1080/0361073x.2018.1449591

Cited by 60 publications

(45 citation statements)

References 30 publications

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“…Review of the titles and abstracts yielded 241 relevant studies for full‐text screening. Thirty‐six studies met all inclusion criteria and were included in this review . A total of 33 studies were included in the meta‐analysis; four of them presented data for both falls and fractures, leaving 20 studies included in the meta‐analysis for falls and 17 studies for fractures …”

Section: Resultsmentioning

confidence: 99%

“…Four studies included a combined group of hospitalized patients with fractures and community‐dwelling individuals without fractures . Two studies reported retrospective data, 20 studies were cross‐sectional, 13 studies were prospective, and 1 study was a randomized controlled trial examining the effect of nutritional supplementation on bone mineral density and risk of falls . Most of the studies were performed in Europe (12 studies), and Asia (12 studies), followed by Australia (5 studies), South America (4 studies), and North America (3 studies) .…”

Section: Resultsmentioning

confidence: 99%

“…The prevalence of sarcopenia varied from 0.3% to 73.0%, depending on the sarcopenia definition applied and the study population. Sarcopenia was diagnosed using one definition or more than one definition . Out of the 36 included studies, EWGSOP (23 studies) was the most commonly used definition, followed by FNIH (7 studies), Baumgartner definition (5 studies), AWGS (4 studies), and IWGS (4 studies) …”

Section: Resultsmentioning

confidence: 99%

“…The quality of 12 falls studies and 14 fracture studies was rated high. Ten studies for falls were rated as low quality . Five studies for fractures were rated as low quality …”

Section: Resultsmentioning

confidence: 99%

“…. Other definitions are based on both low muscle mass and low muscle strength/physical performance: European Working Group on Sarcopenia in Older People (EWGSOP), Asian Working Group for Sarcopenia (AWGS), Foundation for the National Institutes of Health (FNIH), International Working Group on Sarcopenia (IWGS), Society for Sarcopenia, Cachexia, and Wasting Disorders (SCWD), and ESPEN Special Interest Group on ‘cachexia‐anorexia in chronic wasting diseases’ and ‘nutrition in geriatrics’ . In cases where studies applied multiple sarcopenia definitions, results based on the EWGSOP definition were prioritized over the Baumgartner definition and other definitions …”

Section: Methodsmentioning

confidence: 99%

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Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta‐analysis

Yeung

Reijnierse

Pham

et al. 2019

J cachexia sarcopenia muscle

558

379

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Sarcopenia is a potentially modifiable risk factor for falls and fractures in older adults, but the strength of the association between sarcopenia, falls, and fractures is unclear. This study aims to systematically assess the literature and perform a meta‐analysis of the association between sarcopenia with falls and fractures among older adults. A literature search was performed using MEDLINE, EMBASE, Cochrane, and CINAHL from inception to May 2018. Inclusion criteria were the following: published in English, mean/median age ≥ 65 years, sarcopenia diagnosis (based on definitions used by the original studies' authors), falls and/or fractures outcomes, and any study population. Pooled analyses were conducted of the associations of sarcopenia with falls and fractures, expressed in odds ratios (OR) and 95% confidence intervals (CIs). Subgroup analyses were performed by study design, population, sex, sarcopenia definition, continent, and study quality. Heterogeneity was assessed using the I 2 statistics. The search identified 2771 studies. Thirty‐six studies (52 838 individuals, 48.8% females, and mean age of the study populations ranging from 65.0 to 86.7 years) were included in the systematic review. Four studies reported on both falls and fractures. Ten out of 22 studies reported a significantly higher risk of falls in sarcopenic compared with non‐sarcopenic individuals; 11 out of 19 studies showed a significant positive association with fractures. Thirty‐three studies (45 926 individuals) were included in the meta‐analysis. Sarcopenic individuals had a significant higher risk of falls (cross‐sectional studies: OR 1.60; 95% CI 1.37–1.86, P < 0.001, I 2 = 34%; prospective studies: OR 1.89; 95% CI 1.33–2.68, P < 0.001, I 2 = 37%) and fractures (cross‐sectional studies: OR 1.84; 95% CI 1.30–2.62, P = 0.001, I 2 = 91%; prospective studies: OR 1.71; 95% CI 1.44–2.03, P = 0.011, I 2 = 0%) compared with non‐sarcopenic individuals. This was independent of study design, population, sex, sarcopenia definition, continent, and study quality. The positive association between sarcopenia with falls and fractures in older adults strengthens the need to invest in sarcopenia prevention and interventions to evaluate its effect on falls and fractures.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…The quality of 12 falls studies and 14 fracture studies was rated high. Ten studies for falls were rated as low quality . Five studies for fractures were rated as low quality …”

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 3 more Smart Citations

Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta‐analysis

Yeung

Reijnierse

Pham

et al. 2019

J cachexia sarcopenia muscle

558

379

View full text Add to dashboard Cite

show abstract

Older adults with slow sit to stand times show reduced temporal precision of audio–visual integration

et al. 2023

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Sustained integration of sensory inputs over increased temporal delays is associated with reduced cognitive and physical functioning in older adults and adverse outcomes such as falls. Here, we explored the relationship between multisensory integration and a clinically relevant measure of balance/postural control; Sit-to-Stand Time, the efficiency with which an older adult can transition between a seated and a standing posture. We investigated whether temporal multisensory integration was associated with performance on the Five-Times Sit-to-Stand Test (FTSST) in a large sample of 2556 older adults (mean age = 63.62 years, SD = 7.50; 55% female) drawn from The Irish Longitudinal Study on Ageing (TILDA). K-means clustering was applied to FTSST data, yielding three clusters characterised by fast (mean = 10.88 s; n = 1122), medium (mean = 14.34 s; n = 1133) and slow (mean = 18.97 s; n = 301) sit-to-stand times. At wave 3 of TILDA, older adults participated in the Sound Induced Flash Illusion (SIFI), a measure of the precision of temporal audio–visual integration, which included three audio–visual stimulus onset asynchronies (SOAs): 70, 150 and 230 ms. Older adults with the slowest sit-to-stand times were more susceptible to the SIFI at the longest SOA (230 ms) compared to the shortest SOA (70 ms) relative to those with the fastest times (p = 0.02). Older adults who take longer to repeatedly transition from a seated to a standing posture exhibit an expanded temporal binding window for audio–visual events, supporting a link between multisensory perception and balance/postural control in ageing.

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Psoas muscle index is related to hip fracture in osteoporosis: a cross-sectional MRI study

Karatekin

Tekin

2021

Skeletal Radiol

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Severity of sarcopenia is associated with postural balance and risk of falls in community-dwelling older women

Abstract: Sarcopenia negatively affects balance, and both risk and fear of falling in community-dwelling older women. Moreover, this study provides evidence that sarcopenia severity is further associated to reduced balance and imposes an even greater risk of falls in the elderly.

Cited by 60 publications

References 30 publications

Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta‐analysis

Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta‐analysis

Older adults with slow sit to stand times show reduced temporal precision of audio–visual integration

Psoas muscle index is related to hip fracture in osteoporosis: a cross-sectional MRI study

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