Severity of illness and organ dysfunction scoring systems in pediatric critical care: The impacts on clinician's practices and the future

Abstract

Severity and organ dysfunction (OD) scores are increasingly used in pediatric intensive care units (PICU). Therefore, this review aims to provide 1/ an updated state-of-the-art of severity scoring systems and OD scores in pediatric critical care, which explains 2/ the performance measurement tools and the significance of each tool in clinical practice and provides 3/ the usefulness, limits, and impact on future scores in PICU. The following two pediatric systems have been proposed: the PRISMIV, is used to collect data between 2 h before PICU admission and the first 4 h after PICU admission; the PIM3, is used to collect data during the first hour after PICU admission. The PELOD-2 and SOFApediatric scores were the most common OD scores available. Scores used in the PICU should help clinicians answer the following three questions: 1/ Are the most severely ill patients dying in my service: a good discrimination allow us to interpret that there are the most severe patients who died in my service. 2/ Does the overall number of deaths observed in my department consistent with the severity of patients? The standard mortality ratio allow us to determine whether the total number of deaths observed in our service over a given period is in adequacy with the number of deaths predicted, by considering the severity of patients on admission? 3/ Does the number of deaths observed by severity level in my department consistent with the severity of patients? The calibration enabled us to determine whether the number of deaths observed according to the severity of patients at PICU admission in a department over a given period is in adequacy with the number of deaths predicted, according to the severity of the patients at PICU admission. These scoring systems are not interpretable at the patient level. Scoring systems are used to describe patients with PICU in research and evaluate the service's case mix and performance. Therefore, the prospect of automated data collection, which permits their calculation, facilitated by the computerization of services, is a necessity that manufacturers should consider.

A Retrospective Study on the Availability of Arterial Lactate Levels as a Biomarker of Mortality in Critically Ill Children

“…Scoring systems are used to facilitate this comparison (1). The most commonly used mortality scoring systems are 'Pediatric Risk of Mortality' (PRISM) and 'Pediatric Mortality Index' (PIM) (2,3). In addition, the best known scoring system to assess organ failure is the 'Pediatric Logistic Organ Dysfunction' (PELOD) system (4).…”

Editorial: Methods in Pediatric Critical Care 2022

“…The use of scoring systems to predict mortality, mainly in under-five children with frequent nutritional status involvement, can be a determinant factor that could be considered, mainly in emergent countries ( 15 , 16 ). In this edition of Methods in Pediatric Critical Care 2022, Recher et al performed an updated state-of-the-art about the main severity and organ dysfunction scoring systems in pediatric intensive care ( 17 ). These scores can help clinicians understand much better about monitoring and therapeutics attitudes in PICU.…”