Severe tick borne encephalitis with simultaneous brain stem, bithalamic, and spinal cord involvement documented by MRI

Bender, Aaron M.

doi:10.1136/jnnp.2004.040469

Cited by 62 publications

(48 citation statements)

References 11 publications

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“…In the largest study of patients with TBE, only 18 of 102 patients (17.5 %) revealed abnormal findings, which were restricted mainly to the thalamus and occasionally to the cerebellum, nucleus caudatus, basal ganglia and brainstem [15]. These findings were confirmed by several other case reports; in individual patients, involvement of the spinal cord and the radices was also demonstrated [32][33][34][35][36].…”

Section: Imagingsupporting

confidence: 53%

Tick-borne encephalitis: Clinical findings and prognosis in adults

Kaiser

2012

Wien Med Wochenschr

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In middle and eastern European countries, tick-borne encephalitis (TBE) is one of the most important human infections of the central nervous system. TBE virus (TBEV) is mainly transmitted by tick bites and in very rare cases by unpasteurized milk. The incubation period is on an average 7-10 days. A biphasic course of illness with a prodromal period occurs in about two third of patients. In European countries, TBE presents as meningitis in about 50 % of patients, as meningoencephalitis in 40 %, and as meningoencephalomyelitis in 10 %. The severity of TBE increases with age, in children and adolescents, meningitis is the predominant form of the disease. Long-term prognosis is unfavorable in about 40-50 % of patients who suffer from sequelae for months to years, mainly in terms of pareses, ataxia, and other gait disturbances. No specific treatment for TBE is known so far, but TBE can be successfully prevented by active immunization.

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Section: Imagingsupporting

confidence: 53%

Tick-borne encephalitis: Clinical findings and prognosis in adults

Kaiser

2012

Wien Med Wochenschr

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“…As for TBE, our cases never visited foreign countries close to TBE infected area. In addition, typical MRI finding of TBE is spreading symmetrical brainstem and thalamic lesions [4]. The thalamic lesions were not found in our cases.…”

Section: Discussionmentioning

confidence: 92%

Predicting the motor outcome of acute disseminated encephalomyelitis by apparent diffusion coefficient imaging: Two case reports

Kawashima

Matsukawa

Ueki

et al. 2009

Journal of the Neurological Sciences

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“…The thalamus is the region most consistently affected by JE virus and other JE group viruses, including the West Nile virus epidemic in North America and Europe, 14 tick borne encephalitis virus in eastern Europe, 15 and Murray Valley virus in Australia. 16 The JE group viruses has common neurotropism leading to similar neurological symptoms and sequelae.…”

Section: Discussionmentioning

confidence: 99%