“…In patients with thrombocytopenia, the etiology is often unclear and the differential is broad, being comprised of sepsis, disseminated intravascular coagulation, TTP, atypical HUS, heparin- induced thrombocytopenia, other drug-induced thrombocytopenia, and post-transfusion purpura. In vancomycin induced thrombocytopenia, median time to development on thrombocytopenia varied ranging from 2–21 days after initiation of vancomycin [10, 11, 12]. In many reports, the thrombocytopenia developed with the first exposure to vancomycin, whereas in other occurrences it required two exposures.…”