Severe thrombocytopenia in liver transplantation

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“…Platelet sequestration in the liver graft, immunologic reactions, hypersplenism, heparin-induced thrombocytopenia, excessive consumption of platelets, infections, disseminated intravascular coagulation, sepsis, and impaired thrombopoietin production are causative factors of thrombocytopenia in early posttransplant period. [2][3][4] Posttransplant lymphoproliferative disease and tacrolimus-related microangiopathic hemolytic anemia may cause thrombocytopenia less commonly. 2 Most cases are mild and recover in about 1 month.…”