Severe sepsis in cardiac surgical patients

Michalopoulos, Argyris; Stavridis, George; Geroulanos, S

doi:10.1080/110241598750004670

Cited by 58 publications

(47 citation statements)

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“…Leal-Noval et al [16] showed in their study, administration of blood derivatives, in particular red blood cells, was associated with a development of severe postoperative infections (pneumonia). In addition to a higher incidence of postoperative pneumonia, blood transfusion has also been shown to be associated with deep sternal wound infection [17] and severe sepsis [18]. In agreement with these findings we demonstrated blood transfusion to be associated with a higher risk of infectious complication.…”

Section: Discussionsupporting

confidence: 81%

Transfusion associated in-hospital mortality and morbidity in isolated Coronary Artery Bypass Graft surgery

et al. 2009

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AbstractTransfusion after cardiac surgery is very common. This rate varies between institutions and has remained high despite established transfusion guidelines. We analyzed our database of patients who underwent isolated CABG (Coronary Artery Bypass Graft) to determine the predictive factors of homologous transfusion and associated postoperative morbidity, mortality and resource utilization. All 14,152 patients who underwent first-time isolated CABG, with or without cardiopulmonary bypass (CPB) who had postoperative homologous transfusion between February 2002 and March 2008 in Tehran Heart Center, were evaluated retrospectively. Overall, 16.5% of patients received transfusion. Transfused patients demonstrated a significantly higher incidence of postoperative complications (cardiac, infectious, ischemic, reoperation) and mortality (p<0.001). Homologous blood transfusion effect on mortality, morbidity and resource utilization. By Multivariable logistic regression analysis adjusted for confounders: Homologous blood transfusion effect on Mortality (30-days) (OR=3.976, p<0.0001), Prolonged ventilation hours (OR=4.755, p<0.0001), Total ICU hours (β =14.599, p<0.0001), Hospital length of stay (β =1.141, p<0.0001), Post surgery length of stay (β =0.955, p<0.0001). We conclude that the isolated CABG patients receiving blood transfusion have significantly higher mortality, morbidity and resource utilization. Homologous blood transfusion is an independent factor of increased resource utilization, morbidity and mortality.

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Section: Discussionsupporting

confidence: 81%

Transfusion associated in-hospital mortality and morbidity in isolated Coronary Artery Bypass Graft surgery

et al. 2009

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“…Po tego typu operacjach 10-20% pacjentów wymaga hospitalizacji na oddziałach intensywnej terapii, a u 2-50% chorych z tej grupy dochodzi do powikłań septycznych, często zagraża-jących życiu chorego [1]. W ostatnich latach śmiertelność po operacjach kardiochirurgicznych jest nadal wysoka.…”

Section: Wstępunclassified

“…W piśmiennictwie światowym śmiertelność u chorych, u któ-rych rozwinęła się ciężka sepsa, kształtuje się na poziomie 20-70% [1]. W badaniu własnym śmiertelność u pacjentów ze wstrząsem septycznym po operacjach kardiochirurgicznych wyniosła 66,6%, co potwierdza powyższe dane.…”

Section: Dyskusjaunclassified

“…W grupie pacjentów, któ-rzy zmarli -bakterie Gram-ujemne, najczęściej Klebsiella pneumoniae. Uzyskane dane są zgodne z danymi innych autorów [1].…”

Section: Dyskusjaunclassified

“…Przedłużona wentylacja mechaniczna jest czynnikiem ryzyka wystąpienia zapalenia płuc [1,5]. Najczęstszymi patogenami izolowanymi u pacjentów z zapaleniem płuc w badanej grupie były bakterie Gram-ujemne, wśród nich Enterobacteriaceae -podobnie do wyników pochodzących z innych ośrodków [13,14].…”

Section: Dyskusjaunclassified

See 2 more Smart Citations

Analysis of complications among patients hospitalized in the Intensive Care Unit of the Upper Silesian Medical Centre after cardiac surgery in 2010-2011

Gierek¹,

Kaczmarska²,

Budziarz³

et al. 2012

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Post‐ICU Care and Other Complications

2020

Manual of Perioperative Care in Adult Cardiac Surgery

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Severe sepsis in cardiac surgical patients

Abstract: We concluded that severe sepsis mainly developed in cardiac surgery patients with serious operative and postoperative complications and was associated with a longer stay in both ICU and hospital, and a higher mortality.

Cited by 58 publications

References 0 publications

Transfusion associated in-hospital mortality and morbidity in isolated Coronary Artery Bypass Graft surgery

Transfusion associated in-hospital mortality and morbidity in isolated Coronary Artery Bypass Graft surgery

Analysis of complications among patients hospitalized in the Intensive Care Unit of the Upper Silesian Medical Centre after cardiac surgery in 2010-2011

Post‐ICU Care and Other Complications

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