Severe psoriasis, morbid obesity and bariatric surgery

Pérez-Pérez, L.; Allegue, F.; Caeiro, J.L.; Zulaica, J M Fabeiro A

doi:10.1111/j.1365-2230.2009.03406.x

Cited by 32 publications

(15 citation statements)

References 6 publications

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“…27,28 In addition, one study showed that a rapid weight reduction of 10% to 14% of total body weight over 3 to 5 weeks caused CAPSULE SUMMARY d Psoriasis is a systemic disease linked with obesity and it has been suggested that weight loss may improve psoriasis in obese patients. d We report two cases of recalcitrant psoriasis improving after weight loss from gastric bypass surgery.…”

Section: Discussionmentioning

confidence: 98%

Gastric bypass surgery improves psoriasis

Hossler

Maroon

Mowad

2011

Journal of the American Academy of Dermatology

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Section: Discussionmentioning

confidence: 98%

Gastric bypass surgery improves psoriasis

Hossler

Maroon

Mowad

2011

Journal of the American Academy of Dermatology

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“…There is increasing evidence that progressive weight loss can produce significant improvements in the severity of psoriasis 54–58 . Perhaps the most direct evidence that obesity may be causal in psoriasis is the fact that bariatric sugery can produce rapid remission from psoriasis 54,57,58 .…”

Section: Obesity and Psoriasismentioning

confidence: 99%

Obesity and the skin

Shipman

Millington

2011

British Journal of Dermatology

132

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Obesity is a serious global health problem, perhaps the biggest public health issue of our times. Excess body weight may be a factor in carcinogenesis in general, as well as contributing to the pathogenesis of metabolic, cardiovascular and musculoskeletal disorders. Obesity also has many cutaneous features, which form the basis for this review article. Many of these clinical entities are common to the majority of obese patients, e.g. striae distensae, plantar hyperkeratosis and an increased risk of skin infections. However, it may also be associated with poor wound healing, malignant melanoma and an increased risk of inflammatory dermatoses, such as psoriasis, as well as some rarer disorders. Therapeutic interventions for obesity, whether over-the-counter, prescription medicines or surgical interventions, are increasingly commonplace. All of these treatment modalities potentially have dermatological side-effects too.

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“…Data from case reports of overweight patients with psoriasis undergoing weight reduction surgery suggest that psoriasis may improve with weight loss although data are conflicting [71][72][73][74][75][76] . A recent review on the impact of weight loss intervention found that losing weight through decreased caloric intake reduced the severity of psoriasis by a PASI score of about 2.5 [77] .…”

Section: Effect Of Weight Reduction On the Severity Of Psoriasismentioning

confidence: 99%

Psoriasis and Obesity

2016

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Psoriasis is a common chronic inflammatory skin disease with a complex pathogenesis consisting of a genetic component, immune dysfunction, and environmental factors. It is associated with numerous comorbidities including psoriatic arthritis, cardiovascular disease, metabolic syndrome, and obesity. Evidence suggests that obesity is a risk factor for incident psoriasis, aggravates existing psoriasis, and that weight reduction may improve the severity of psoriasis in overweight individuals. Excess body weight may interfere with the medical treatment used in psoriasis and adds to the cardiovascular risk profile in these patients, which underscores the importance of effective weight control regimens. In this review we examine the current literature with regard to the association between obesity and psoriasis.

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Severe psoriasis, morbid obesity and bariatric surgery

Cited by 32 publications

References 6 publications

Gastric bypass surgery improves psoriasis

Gastric bypass surgery improves psoriasis

Obesity and the skin

Psoriasis and Obesity

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