Severe pediatric head injuries (I). Epidemiology, clinical manifestations and course

Alvarez, José Manuel López; Lemaur, M.E. Valerón; Quevedo, O. Pérez; Cañal, José María Limiñana; Laguna, Alberto; Llapurt, E. Consuegra; Casas, A. MorÃ3n Saén de; Jorge, R. González

doi:10.1016/j.medine.2011.02.002

Cited by 1 publication

(1 citation statement)

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“…Although children after TBI have a higher survival rate than adults, sequelae are more devastating in children. [17] Acidosis may cause neural death by disrupting acid-base homeostasis in brain tissue. [18] Therefore, the presence of acidosis has been accepted as an important indicator of morbidity and mortality.…”

Section: Discussionmentioning

confidence: 99%

How Important Are Arterial Blood Gas Parameters for Severe Head Trauma in Children?

Kayabaş

Şahin

2022

Journal of Contemporary Medicine

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Aim: Our aim in this study is to consider the relationship between arterial blood gas (ABG) parameters and prognosis in severe head trauma in children. Material and Method:Patients younger than 17 years of age with a Glasgow Coma Scale (GCS) of 8 and below with a history of head trauma were retrospectively analyzed. The relation of ABG parameters taken at the time of admission with mortality was examined. Independent sample T-test was used for pH, PCO2 and base extract (BE) parameters in ABG, and Mann Whitney U test was used for PO2 and lactate parameters.Results: 48 patients were included in the study. Gender, age, admission blood pressure arterial values, GCS and Abbreviated Injury Scale (AIS) scores, length of stay in intensive care, and the surgical application did not differ statistically between the patient groups who died and survived. Ph and PO2 values were lower, PCO2, lactate, and BE values were found to be higher in the deceased patient group compared to the living patient group. The presence of acidosis, hypercapnia, or hyperlactatemia according to ABG values in the patient group who died was statistically significantly higher. Conclusion:In our study, we found that the presence of acidosis, hypercapnia, and hyperlactatemia in patients according to ABG values increased mortality. We found that high PCO2 and lactate values are specific indicators of poor prognosis. We think that PCO2 and lactate measured in arterial blood may be biomarkers that can determine the prognosis.

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Section: Discussionmentioning

confidence: 99%