Severe pancytopenia as presenting feature in newly diagnosed multiple myeloma (NDMM): a rare presentation.

Vriendt, Ciel De

doi:10.26226/morressier.5a54bfead462b80290b5648c

Cited by 1 publication

(1 citation statement)

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“…17 After a thorough review of literature, there were only two similar studies done in the same field, to the best of our knowledge, although there were handful of case reports. 8,15,16 In the study of Sridevi et al a total of 10 cases which presented with pancytopenia, the mean age being 66.3 years with higher male preponderance. Out of all the symptoms, fatigue and weakness were the most common and pallor was the most common sign.…”

Section: Discussionmentioning

confidence: 99%

Pancytopenia as the initial presenting feature in multiple myeloma: a case series

et al. 2023

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Multiple myeloma is a plasma cell neoplasm characterized by abnormal proliferation of clonal cells in the bone marrow. Anaemia is generally the most common feature from hematologic aspect and bone pain being the other important symptom, but pancytopenia as the presenting feature is unusual. Here, we shared our experience of 3 cases with non-specific symptoms with pancytopenia which on through evaluation revealed our diagnosis. A hospital based observational descriptive case series was conducted wherein all the cases of multiple myeloma presenting with pancytopenia were included. Complete blood picture, peripheral smear, bone marrow aspirate and serum protein electrophoresis were reviewed and analysed. Pancytopenia as the initial presenting feature of multiple myeloma is an unique manifestation and diagnosing such cases require high degree of suspicion to avoid delay in the initiation of treatment.

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Section: Discussionmentioning

confidence: 99%