Severe ovarian hyperstimulation syndrome requiring recurrent large-volume paracenteses until 21 weeks’ gestation: a case report

Henshaw, Chelsea; Kirschen, Gregory W.; Chen, Lucy; Vaught, Arthur J.; Cameron, Katie; Christianson, Mindy S.

doi:10.1016/j.xfre.2022.07.002

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2023

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“…While the pathogenesis is poorly understood, vasoactive particles, including cytokines, tumor necrosis factor-α, endothelin-1, the renin-angiotensin system, and vascular endothelial growth factor (VEGF), have been implicated [6][7][8]. These cytokines have been associated with increased vascular permeability, especially within the peritoneal vasculature.…”

Section: Discussionmentioning

confidence: 99%

Severe Ovarian Hyperstimulation Syndrome in the Setting of In Vitro Fertilization Treatment

Ayllon¹,

Hernandez²,

Nagi³

et al. 2023

Cureus

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Ovarian hyperstimulation syndrome (OHSS) is one of the complications of pharmacological ovarian stimulation used in fertility treatments. This syndrome is characterized by increased vascular permeability secondary to stimulation, resulting in a fluid shift from the intravascular space to the third-space compartments. Patients developing OHSS can experience severe complications, including ascites, pleural effusions, and shock. Here, we present a case of OHSS in the setting of recent transvaginal oocyte retrieval, leading to severe ascites, pleural effusion, and hypotension requiring urgent intervention.

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Section: Discussionmentioning

confidence: 99%