Severe Odontogenic Infections, Part 1: Prospective Report

Flynn, Thomas R.; Shanti, Rabie M.; Levi, Michael H.; Adamo, Arthur K.; Kraut, Richard A.; Trieger, N

doi:10.1016/j.joms.2006.03.015

Cited by 234 publications

(225 citation statements)

References 26 publications

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“…A recent study by Thomas [27] demonstrated that aerobic organisms outnumbered anaerobes by almost 2:1 ratio; our study had exactly opposite results. Aerobic organisms were only 38.89 % of positive cases.…”

Section: Microorganismscontrasting

confidence: 71%

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Management of Odontogenic Space Infection with Microbiology Study

Singh

Kambalimath

Gupta

2014

J. Maxillofac. Oral Surg.

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Introduction Dental infection has plagued humankind for as long as our civilization has been a fight against microorganisms by man dates back to ancient civilization. The discoveries of antibiotics are encouraging trends towards conquest of the microbial infection. Materials and Methods This study emphasizes the detection of pathogenic microorganisms by microbiological examination and culture of specimens representative of the infection, importance of early and correct diagnosis of infections, prompt treatment and supportive care. Results The age group most commonly involved was in the third and fourth decades of life. Extraction followed by incision and drainage was done. The most commonly involved space was submandibular followed by buccal space. Thirty isolates were obtained. 43 % of the strains were strict anaerobes and 39 % were aerobes, with mixed growth was seen in 18.52 %. Amongst aerobes alpha hemolytic Streptococcus aureus and Peptostreptococcus as anaerobes were the most predominant followed by Bacteroides and Prevotella. Mixed aerobic and anaerobic isolates were obtained from 18.52 % of total cases. Overall resistance to Penicillin was 22 %, amongst aerobes. Conclusion Amoxicillin and Clavulanic acid combination performed better, as 100 % strains were sensitive to it. The results of this study saw a changing trend in terms of predominance of anaerobic bacteria over aerobic ones.

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Section: Microorganismscontrasting

confidence: 71%

“…Various literature reports that many species of organisms were resistant to Penicillin [27][28][29]. However most patients were clinically well by the time Penicillin resistance was discovered.…”

Section: Antibiotic Sensitivitymentioning

confidence: 99%

Management of Odontogenic Space Infection with Microbiology Study

Singh

Kambalimath

Gupta

2014

J. Maxillofac. Oral Surg.

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“…Trismus must therefore be regarded as a signifi cant indicator of severe odontogenic infection. 40 In addition bacterial metabolites, along with endotoxins and exotoxins, may enter the blood stream. These affect the thermoregulatory centre in the hypothalamus leading to an increased body temperature, seen clinically as pyrexia.…”

Section: Current Prescribing Practicesmentioning

confidence: 99%

“…Clinical signs of pyrexia, trismus, signifi cant regional lymphadenopathy, gross facial swelling, closure of the eye, dysphagia, tachycardia and rigors should be regarded as indicators of systemic response to infection and adjunctive antibiotic therapy is always indicated. 7,[14][15][16]29,[31][32][33][34][35][37][38]40,42,43 Where there is systemic involvement treatment involves drainage of the abscess primarily to allow the release of pus, reduce the overall number of microorganisms, decrease the tissue pH, increase oxygen diffusion and allow antibiotics to penetrate. 14 This is followed by removal of the cause of the infection and adjunctive antibiotic therapy.…”

Section: Current Prescribing Practicesmentioning

confidence: 99%

“…Its use, however, is now increasing and it has been suggested that this could be the antibiotic of choice for adjunctive management of acute dentoalveolar abscesses. 15,18,40,59,63,65,66 For the past 15 years it has been used as a penicillin alternative for antibiotic prophylaxis for the prevention of bacterial endocarditis in patients either allergic to penicillin or those who have had a recent course of penicillin, 67,68 highlighting its spectrum of activity in combating the relevant oral fl ora. PMC can be caused by an overgrowth of Clostridium diffi cile, which is found in the colon as a normal commensal in approximately 2-3% of healthy adults.…”

Section: Clindamycinmentioning

confidence: 99%

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