Severe obstructive sleep apnea diagnosed after non-arteritic anterior ischaemic optic neuropathy in a young man

Lei, Shaobo; Micieli, Jonathan A

doi:10.1136/bcr-2019-232512

Cited by 3 publications

(2 citation statements)

References 18 publications

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“…On the other hand, stringently adherent CPAP therapy also significantly improved VEP in patients with OSA [ 67 ]. Given the strong association between OSA and NAION, PSG may be suggested in patients with newly diagnosed NAION, especially in younger patients, as well as those without other risk factors [ 68 ].…”

Section: Osa-associated Complications In Optic Nervementioning

confidence: 99%

Ocular Complications of Obstructive Sleep Apnea

Liu

Chiu

Wang

et al. 2021

JCM

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Obstructive sleep apnea (OSA), the most common form of sleep-disordered breathing, is characterized by repetitive episodes of paused breathing during sleep, which in turn induces transient nocturnal hypoxia and hypercapnia. The high prevalence of OSA and its associated health consequences place a heavy burden on the healthcare system. In particular, the consequent episodic oxygenic desaturation/reoxygenation series and arousals from sleep in patients with OSA have the potential to trigger oxidative stress, elevated systemic inflammatory responses, and autonomic dysfunction with sympathetic activation. Given these adverse side-effects, OSA is highly correlated to many eye diseases that are common in everyday ophthalmic practices. Some of these ocular consequences are reversible, but they may permanently threaten a patient’s vision if not treated appropriately. Here, this article seeks to review the ocular consequences and potential pathophysiologic associations in patients with OSA. Understanding these OSA-related eye diseases may help clinicians provide comprehensive care to their patients.

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Section: Osa-associated Complications In Optic Nervementioning

confidence: 99%

Ocular Complications of Obstructive Sleep Apnea

Liu

Chiu

Wang

et al. 2021

JCM

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“…OSA is also a concern in younger patients below 50 years of age and NAION has been found to be the presenting condition of severe sleep apnea in younger individuals. 33 Although there is no established treatment for NAION, efforts should be focused on identification and optimization of risk factors including OSA to reduce the likelihood of fellow-eye involvement, which can be devastating for these patients.…”

Section: Osa and Naionmentioning

confidence: 99%

<p>Neuro-Ophthalmological Manifestations of Obstructive Sleep Apnea: Current Perspectives</p>

Farahvash

Micieli

2020

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Obstructive sleep apnea (OSA) is a disease of obstructed airways during sleep that significantly impacts the quality of life and increases the risk of various systemic diseases. OSA has been studied as a risk factor for a number of neuro-ophthalmic conditions and a strong relationship has been established with non-arteritic anterior ischemic optic neuropathy (NAION). The incidence of glaucoma and stroke have also been significantly associated with OSA and are conditions that may also be seen by neuro-ophthalmologists. Patients with NAION have a significantly higher incidence of OSA and OSA diagnosis significantly increases the risk for NAION development. Non-compliance with continuous positive airway pressure (CPAP) in OSA patients has also been found to be a risk factor for fellow-eye involvement and there is increasing evidence to suggest that every patient with NAION should be formally evaluated with polysomnography. The relationship between OSA and idiopathic intracranial hypertension (IIH) has also been studied, but the relationship between these two conditions is less clear. There is insufficient evidence to recommend routine eye examinations in OSA patients for papilledema and conducting a sleep study for a newly diagnosed IIH patient should be left to the discretion of the clinician based on other symptoms and risk factors of OSA.

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