Severe Nonfebrile Dengue Infection in an Adolescent After Postoperative Kidney Transplantation: A Case Report

Tangnararatchakit, Kanchana; Tirapanich, Wiwat; Tapaneya-Olarn, W; Sumethkul, V.; Sirachainan, Nongnuch; Watcharananan, Siriorn P.; Leenanupunth, Charoen; Yoksan, Sutee; Chuansumrit, Ampaiwan

doi:10.1016/j.transproceed.2011.11.025

Cited by 29 publications

(20 citation statements)

References 12 publications

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“…More recently, Nasim et al (6) studied 258 renal transplant patients with positive serology for dengue, wherein only 4% presented with severe disease. Other authors (12) reported a case with a clinical profi le similar to ours, but with a less severe presentation of dengue.…”

Section: Casesupporting

confidence: 80%

Severe dengue in the early postoperative period after kidney transplantation: two case reports from Hospital Geral de Fortaleza

Maia

Brasil

Esmeraldo

et al. 2015

Rev. Soc. Bras. Med. Trop.

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Dengue is an arbovirosis that ranges from an asymptomatic presentation to a more severe disease, which is characterized by a vascular leakage syndrome where abdominal pain is a major symptom. Transplant recipients are immunosuppressed and are less likely to develop a severe form of the disease because of a reduction in immune-mediated responses that trigger plasma extravasation events. Herein, we report two cases of severe dengue in the early postoperative period of two kidney transplant recipients. Considering the severity of the cases, we emphasize the importance of dengue screening immediately before transplantation in areas endemic for the disease.

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Section: Casesupporting

confidence: 80%

Severe dengue in the early postoperative period after kidney transplantation: two case reports from Hospital Geral de Fortaleza

Maia

Brasil

Esmeraldo

et al. 2015

Rev. Soc. Bras. Med. Trop.

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“…The occurrence of DHF in the early postoperative period caused potential danger to our patients, similar to cases reported before. 5,7 In our study, the two patients with DHF in the first week after transplantation had thrombocytopenia, platelet dysfunction, and coagulopathy resulting in profuse bleeding around the graft, leading to circulatory collapse that required hematoma drainage, and one lost the graft, demonstrating the severity of the infection in the early posttransplant period. The other one needed dialysis for 3 weeks before renal function recovery.…”

mentioning

confidence: 64%

“…6 Dengue can also be transmitted to the recipients from the donor, and even patients who have severe complications, such as hemorrhage, usually have good recovery. 7 The objective of this article is to describe the clinical manifestations and renal involvement in cases of dengue in renal transplant patients.…”

mentioning

confidence: 99%

Dengue Fever Among Renal Transplant Recipients: A Series of 10 Cases in a Tropical Country

Costa

Silva

Jacinto

et al. 2015

The American Journal of Tropical Medicine and Hygiene

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“…This group consisted of 29 patients (Male 48.3%), from six countries, across six studies [3–5, 7, 13, 14]. As explained earlier in the text, two studies were left out in forming the composite group.…”

Section: Resultsmentioning

confidence: 99%

“… Abbreviations : LFT liver function tests, RT PCR reverse transcriptase polymerase chain reaction, NS1 non specific antigen 1 a Prevalence of non-transplant population given by Casali CG et al [14] b Frequency of DHF given in Casali et al is 3.7%. The mortality of DHF is 3.21% while that of DF is 0.026%.…”

Section: Resultsmentioning

confidence: 99%

Dengue fever in renal transplant patients: a systematic review of literature

2017

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BackgroundDengue fever in renal transplanted patients has not been studied well, and we review all the literature about episodes dengue fever in renal transplant patients.MethodsThe aim was to describe clinico-pathological characteristics, immunosuppressive protocols, need renal outcome and mortality. PubMed, LILACS, Google Scholar and Research Gate were searched for “Dengue” and “Renal/Kidney Transplantation” with no date limits. Hits were analyzed by two researchers separately.ResultsFever, myalgia, arthralgia and headache was significantly lower than normal population, while pleural effusions and ascites were observed more. Incidence of severe dengue is significantly higher among transplant patients in this review, as well as they had a significantly higher mortality (8.9% vs 3.7%, p = 0.031). Age, period after transplantation and immunosuppressive profile had no effect on disease severity, mortality or graft out come. Presence of new bleeding complications and ascites was associated with more severe disease (p < 0.001 and p = 0.005), death (p = 0.033) or graft loss (p = 0.035). Use of tacrolimus was associated with new bleeding complications (p = 0.027), and with ascites (p = 0.021), but not with thrombocytopenia. 25% of patients with primary disease fail to mount an IgG response by 15 weeks of the illness. 58.9% had graft dysfunction during illness. Postoperative transplanted patients were at risk of severe disease and unfavorable outcome.ConclusionsThe physical and laboratory findings in dengue fever in renal transplanted patients differ from the general population. Some degree of graft dysfunction is common during the illness, but only a minority develops graft failure.

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Severe Nonfebrile Dengue Infection in an Adolescent After Postoperative Kidney Transplantation: A Case Report

Cited by 29 publications

References 12 publications

Severe dengue in the early postoperative period after kidney transplantation: two case reports from Hospital Geral de Fortaleza

Severe dengue in the early postoperative period after kidney transplantation: two case reports from Hospital Geral de Fortaleza

Dengue Fever Among Renal Transplant Recipients: A Series of 10 Cases in a Tropical Country

Dengue fever in renal transplant patients: a systematic review of literature

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