2023
DOI: 10.1590/0037-8682-0228-2023
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Severe mpox in patients with advanced AIDS: long-term disease and fatal outcome

Luís Arthur Brasil Gadelha Farias,
Pablo Eliack Linhares de Holanda,
Ana Danielle Tavares da Silva
et al.

Abstract: Herein, we report two cases of severe mpox in patients with advanced acquired immunodeficiency syndrome from Brazil who developed atypical lesions and prolonged illness, one of whom had a fatal outcome. Both patients experienced serious complications involving the perianal and genital regions and prolonged disease with persistent viremia.

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“…There is no data about the other. - Yes Caria, 2023 [ 38 ] Brazil 1(+) Uncontrolled HIV, (CD4 + count of 173/µL) - Yes Carrubba, 2023 [ 37 ] 2 (+) Uncontrolled HIV, (CD4 + count of < 100 cells/µL) and VL > 40,000 copies per mL - Yes Menezes, 2022 [ 36 ] Brazil 1(+) Uncontrolled HIV, (CD4 count was 5 cells/µL with undetectable VL) - - Farias, 2023 [ 35 ] Brazil 1(+) Uncontrolled HIV, (CD4 + cell count < 50 cells/µL) - Yes Rajme-López, 2023 [ 17 ] Mexico 3(+) Uncontrolled HIV, (The CD4 + cell count < 200 cells/µL and the unsuppressed RNA VL) Yes, all of them are Suspected with IRIS No Warner, 2023 [ 18 ] USA 1(+) Uncontrolled HIV (the CD4 + cell count is 12 cells/µL with unsuppressed RNA VL) Yes Yes Triana-González, 2023 [ 32 ] Mexico 5 (4+) and (1-) Uncontrolled HIV, (Four had a CD4 + cell count < 200 cells/µL and an unsuppressed VL), and one was non-HIV immunocompromised - Yes Petti, 2023 [ 19 ] USA 2 (+) ...…”
Section: Resultsmentioning
confidence: 99%
“…There is no data about the other. - Yes Caria, 2023 [ 38 ] Brazil 1(+) Uncontrolled HIV, (CD4 + count of 173/µL) - Yes Carrubba, 2023 [ 37 ] 2 (+) Uncontrolled HIV, (CD4 + count of < 100 cells/µL) and VL > 40,000 copies per mL - Yes Menezes, 2022 [ 36 ] Brazil 1(+) Uncontrolled HIV, (CD4 count was 5 cells/µL with undetectable VL) - - Farias, 2023 [ 35 ] Brazil 1(+) Uncontrolled HIV, (CD4 + cell count < 50 cells/µL) - Yes Rajme-López, 2023 [ 17 ] Mexico 3(+) Uncontrolled HIV, (The CD4 + cell count < 200 cells/µL and the unsuppressed RNA VL) Yes, all of them are Suspected with IRIS No Warner, 2023 [ 18 ] USA 1(+) Uncontrolled HIV (the CD4 + cell count is 12 cells/µL with unsuppressed RNA VL) Yes Yes Triana-González, 2023 [ 32 ] Mexico 5 (4+) and (1-) Uncontrolled HIV, (Four had a CD4 + cell count < 200 cells/µL and an unsuppressed VL), and one was non-HIV immunocompromised - Yes Petti, 2023 [ 19 ] USA 2 (+) ...…”
Section: Resultsmentioning
confidence: 99%