Severe Measles Pneumonitis in Adults

Gubler, Jacques; Lüthy, Regina; Oelz, O

doi:10.1093/clinids/21.4.1060

Cited by 3 publications

(2 citation statements)

References 2 publications

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“…Among the dreaded complications of measles are pneumonitis and bacterial pneumonia secondary to transient immune suppression or increased host vulnerability to other pathogens by eliminating the antibody repertoire observed in immune amnesia [14,[65][66][67]. Similarly, lymphopenia in the present case might reflect the dysregulated cellular immune response in measles.…”

Section: Discussionmentioning

confidence: 67%

First Disease and the Great Imitator: A Diagnostic Dilemma with Ancient Maladies

Imad¹,

Lakanavisid²,

Pisutsan³

et al. 2022

Preprint

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Fever and rash as manifestations of infection by microorganisms are collectively known as febrile exanthem. Viruses are more frequently associated with febrile exanthema, and often these symptoms are thus impetuously termed viral exanthem. However, bacteria represent a frequently overlooked infectious etiology causing rash in humans. In addition, certain microbes may exhibit pathognomonic features that erupt during illness and facilitate clinical diagnosis. Conversely, coinfections often obscure the clinical characteristics of the primary disease and further challenge clinicians attempting to reach a diagnosis. We retrospectively looked at de-identified clinical data of a patient who presented to the Hospital for Tropical Diseases in Bangkok in July 2019 with complaints of fever and rash. The case involved a 35-year-old who presented with a 3-day history of fever, respiratory symptoms, myalgia, conjunctivitis, diarrhea, and a generalized maculopapular rash. On examination, the patient was febrile, tachycardic, and tachypneic, with a mean arterial pressure of 95 mmHg. A differential white blood cell count showed: leukocytes, 5800/µL; neutrophils, 4408/µL; lymphocytes, 406/µL; and platelets, 155,000/µL. Striking findings involving the integumentary system included Koplik’s spots and generalized maculopapular rash. Further serology revealed positive immunoglobulin (Ig)M and IgG for both measles and rubella virus, including reactive serology for Treponema pallidum. Here we describe the clinical course and management of this patient.

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Section: Discussionmentioning

confidence: 67%

First Disease and the Great Imitator: A Diagnostic Dilemma with Ancient Maladies

Imad¹,

Lakanavisid²,

Pisutsan³

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…Among the dreaded complications of measles are pneumonitis and bacterial pneumonia secondary to transient immune suppression or increased host vulnerability to other pathogens consequent on the elimination of the antibody repertoire observed in immune amnesia [ 14 , 56 , 57 , 58 ]. Similarly, lymphopenia in the present case might reflect the dysregulated cellular immune response in measles.…”

Section: Discussionmentioning

confidence: 99%

A Case Report of Secondary Syphilis Co-Infected with Measles: A Diagnostic Dilemma with Fever and Rash

et al. 2022

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Fever and rash as manifestations of infection by microorganisms are collectively known as febrile exanthem. Since viruses are more frequently associated with fever and rash, these symptoms are thus impetuously termed viral exanthem. However, bacteria represent a frequently overlooked infectious etiology causing rash in humans. In addition, certain microbes may exhibit pathognomonic features that erupt during illness and facilitate clinical diagnosis. Conversely, coinfections often obscure the clinical characteristics of the primary disease and further challenge clinicians attempting to reach a diagnosis. We retrospectively looked at de-identified clinical data of a patient who presented to the Hospital for Tropical Diseases in Bangkok in July 2019 with complaints of fever and rash. The case involved a 35-year-old who presented with a 3-day history of fever, respiratory symptoms, myalgia, conjunctivitis, diarrhea, and a generalized maculopapular rash. On examination, the patient was febrile, tachycardic, and tachypneic, with a mean arterial pressure of 95 mmHg. A differential white blood cell count showed: leukocytes, 5800/µL; neutrophils, 4408/µL; lymphocytes, 406/µL; and platelets, 155,000/µL. Striking findings involving the integumentary system included Koplik’s spots and generalized maculopapular rash. Further serology revealed positive immunoglobulin (Ig)M and IgG for both measles and rubella virus, including reactive serology for Treponema pallidum. Here we describe the clinical course and management of this patient.

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Measles and Varicella Pneumonia

Johnston

Community-Acquired Pneumonia

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Severe Measles Pneumonitis in Adults

Cited by 3 publications

References 2 publications

First Disease and the Great Imitator: A Diagnostic Dilemma with Ancient Maladies

First Disease and the Great Imitator: A Diagnostic Dilemma with Ancient Maladies

A Case Report of Secondary Syphilis Co-Infected with Measles: A Diagnostic Dilemma with Fever and Rash

Measles and Varicella Pneumonia

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