Severe Kala-azar and seric level of IL-6: case reports

Brito, Gilmara da Rocha; Marreiros, Aécio da Silva; Araujo, Izael Francisco de Brito; Júnior, Raimundo Gerônimo da Silva; Sene, Ingridi de Souza; Braz, Débora Cavalcante

doi:10.12662/2317-3076jhbs.v8i1.3035.p1-4.2020

Cited by 1 publication

(1 citation statement)

References 10 publications

(21 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Human visceral leishmaniasis (VL) known as calazar 1 , 2 or kala-azar 3 , 4 (“black fever”), is a chronic zoonosis, 5 of great importance for public health 6 due to its epidemiological diversity, 7 and in the absence of adequate treatment, results in fatal cases for humans. 8 VL has high mortality, especially in untreated people and malnourished children, is also seen developing in individuals with acquired immunodeficiency virus (HIV) infection.…”

Section: Introductionmentioning

confidence: 99%

Visceral Leishmaniasis Associated with HIV Coinfection in Pará, Brazil

Júnior¹,

Gomes²,

Carvalho³

et al. 2023

HIV

View full text Add to dashboard Cite

Introduction Human visceral leishmaniasis (VL) is a zoonosis of great importance to public health due to its epidemiological diversity, with emphasis on the possibility of aggravation by coinfection with the human immunodeficiency virus (HIV). Objective The aim was to study the epidemiological characteristics of VL cases associated with HIV coinfection in Pará. Methods. Reported cases of VL from January 2006 to December 2016 were investigated. A descriptive epidemiological method related to age, gender, area of residence and coinfection with HIV was used. To calculate variance and test equity, the F -test (Fisher) was performed. To observe the influence of one aspect on another, the chi-square was used to verify if there was dependence or independence between the variables. Results A total of 1171 cases of VL were reported during the study period. There was an annual mean of LV of 94.9, with a statistical difference (p<0.05) between age groups, with the highest number of cases being observed in children aged 1 to 4 years (27.16%). Males and the urban area had a higher number of cases. There were 57 cases of VL/HIV coinfection, with emphasis on the year 2013 and the municipality of Santarém, which had the highest number of cases. During the ten years studied, there was a correlation between coinfection VL/ HIV, with significant differences between patients with and without HIV who contracted VL (p<0.001). Conclusion The data reveal the endemic nature of VL in the region, with a high percentage of infection in children living in urban areas. Although the studied region is not identified as a predominant area of HIV cases, this study showed a high annual average (10.3) of cases of VL/HIV coinfection being the first time that cases of VL/HIV coinfection were reported in the Mesoregion of the Lower Amazon and Southwest Pará.

show abstract