Severe Jarisch-Herxheimer Reaction (JHR) in a leptospirosis patient: A case report

Zhao, Ruo-Yan; Liu, Meng-Die; Lin, Ying-Xin; Huang, Lei

doi:10.1016/j.heliyon.2024.e24538

Heliyon

2024

DOI: 10.1016/j.heliyon.2024.e24538

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Severe Jarisch-Herxheimer Reaction (JHR) in a leptospirosis patient: A case report

Ruo-Yan Zhao,

Meng-Die Liu,

Ying-Xin Lin

et al.

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2024

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A case of leptospirosis in transcarpathia complicated with Jarisch-Herxheimer reaction

Vysochanska,

Babych,

Kohutych

et al. 2024

Wiad Lek

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A case report of Jarisch-Herxheimer (JHR) reaction on a 10th day of Leptospirosis caused by Leptospira Pomona. JHR occurs as a complication of an antibiotic treatment of various spirochetes and may lead to respiratory distress syndrome, renal failure, hepatic insufficiency, and multiple organ failure. This case represents a skin and cardio-vascular form of JHR with no lung involvement. The patient was treated with benzylpenicillin and low dexamethasone doses for 5th day of the disease with a shift to ceftriaxone and high doses of methylprednisolone. The fastest diagnosis of a sporadic zoonotic disease, early start of antibiotic therapy, and adequate doses of corticosteroids are key to the successful treatment of leptospirosis.

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A case of leptospirosis in transcarpathia complicated with Jarisch-Herxheimer reaction

Vysochanska,

Babych,

Kohutych

et al. 2024

Wiad Lek

View full text Add to dashboard Cite

show abstract

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Severe Jarisch-Herxheimer Reaction (JHR) in a leptospirosis patient: A case report

Cited by 1 publication

References 15 publications

A case of leptospirosis in transcarpathia complicated with Jarisch-Herxheimer reaction

A case of leptospirosis in transcarpathia complicated with Jarisch-Herxheimer reaction

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