2002
DOI: 10.1002/ccd.10046
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Severe intravascular hemolysis after transcatheter closure of a large patent ductus arteriosus using the Amplatzer duct occluder: Successful resolution by intradevice coil deployment

Abstract: A 21-year-old female developed severe unremitting intravascular hemolysis following closure of a large patent ductus arteriosus using an Amplatzer duct occluder. Percutaneous deployment of fibered platinum coils within the nitinol wire cage of the Amplatzer duct occluder abolished the residual shunt through the device and resulted in cessation of intravascular hemolysis and reversal of its adverse sequelae.

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Cited by 19 publications
(12 citation statements)
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References 55 publications
(54 reference statements)
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“…In general, this is seen with the use of coils and typically occurs at a rate of approximately 0.8% [6,7]. When using the Amplatzer duct occluder, hemolysis is even less common [6]. Hemolytic anemia in our patient most likely was due to high-velocity blood flow going through the fine wire mesh of the device placed in the ductus.…”
Section: Discussionmentioning
confidence: 91%
See 1 more Smart Citation
“…In general, this is seen with the use of coils and typically occurs at a rate of approximately 0.8% [6,7]. When using the Amplatzer duct occluder, hemolysis is even less common [6]. Hemolytic anemia in our patient most likely was due to high-velocity blood flow going through the fine wire mesh of the device placed in the ductus.…”
Section: Discussionmentioning
confidence: 91%
“…Clinically overt hemolysis following transcatheter PDA closure is a rare complication and is related to residual shunt. In general, this is seen with the use of coils and typically occurs at a rate of approximately 0.8% [6,7]. When using the Amplatzer duct occluder, hemolysis is even less common [6].…”
Section: Discussionmentioning
confidence: 98%
“…3 Recently intradevice coil deployment has also been reported to cope with such complications. 25 The major overall limiting factor may be the high cost of the Amplatzer device, but its different advantages should probably outweigh its price.…”
Section: Discussionmentioning
confidence: 99%
“…Safety data suggest that complications are unusual, but include the same problems encountered with coils: device embolization, left pulmonary artery stenosis, protrusion into the aorta, and hemolysis. Interestingly, hemolysis has been terminated anecdotally by placing a coil inside the device [46].…”
Section: Amplatzer Devicesmentioning
confidence: 99%