Severe<i>Demodex</i><i>folliculorum</i>–Associated Oculocutaneous Rosacea in a Girl Successfully Treated With Ivermectin

Brown, Megan; Hernández‐Martín, Ángela; Clément, A; Colmenero, Isabel; Torrelo, Antonio

doi:10.1001/jamadermatol.2013.7688

Cited by 44 publications

(28 citation statements)

References 9 publications

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“…Complete resolution was achieved 90 days after initiation of treatment independently of the intensity of the infection. Brown et al [57] noted the case of a 12-year-old girl with serious ocular demodicosis and rosacea, who improved a month after receiving single-dose 12-mg therapy with ivermectin.…”

Section: Diagnosismentioning

confidence: 99%

Blepharitis and Demodex spp. infection

et al. 2017

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According to the latest reports Demodex mites appear to play an important role in the pathogenesis of chronic blepharitis. Demodex mites are cosmopolitan and are present in many species of mammals. In this paper we describe two species that are found in humans: Demodex folliculorum and D. brevis. Infection occurs during direct contact with an affected person and also through contact with dust containing eggs of the parasite, through contact with bed linen, as well as cosmetics used together with an affected person. Treatment of chronic blepharitis caused by D. folliculorum and D. brevis is difficult and time consuming. Some improvement can be achieved after topical application of yellow mercury ointment, sulphuric ointment, camphor oil, crotamiton, cholinesterase inhibitors, sulfacetamide, steroids, antibiotics and antifungal drugs. Good results have been achieved with oral ivermectin and permethrin cream. However, the best results were observed after treatment with metronidazole.

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Section: Diagnosismentioning

confidence: 99%

Blepharitis and Demodex spp. infection

et al. 2017

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“…ile ilişkili blefarit olgularında günümüzde önerilen tedavi terpinen-4-ol içeren çay ağacı yağı losyonlarının kullanıl-masıdır (12) . Tek doz oral ivermektin ile tedavinin de etkili olduğunu gös-teren olgular bulun-maktadır (13) .…”

Section: Olguunclassified

A Case of Demodex folliculorum Associated with Blepharitis

Zorbozan¹,

Okut²,

Ünver³

et al. 2016

TMCD

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“…Various pharmaceutical agents have been used to reduce the Demodex mite population in humans including topical tretinoin, gamma benzene hexachloride lotion, 1% permethrin cream rinse,10% povidone–iodine, 75% and 100% alcohol, 50% baby shampoo, 4% pilocarpine, 100% tea tree oil, 100% caraway oil, and 100% dill weed oil, crotamiton 10% cream, Ivermectin . Photodynamic therapy has also been used for this purpose .…”

Section: Introductionmentioning

confidence: 99%

Study of Demodex mites: Challenges and Solutions

Lacey

Russell‐Hallinan

Powell

2015

Acad Dermatol Venereol

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Demodex mites are the largest and most complex organisms of the skin microflora. How they interact with the innate and adaptive immune systems is unknown. Their potential to have a pathogenic role in the causation of human skin disorders causes continued speculation. With growing interest in the microflora of human skin and its relevance to cutaneous health, the role of Demodex mites needs to be better understood. The main challenges facing scientists investigating the role of these organisms and possible solutions are reviewed under the following headings: (1) Determining the mite population in skin, (2) Transporting, extracting and imaging live mites, (3) Maintaining mites viable ex vivo and (4) Establishing methods to determine the immune response to Demodex mites and their internal contents.

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SevereDemodexfolliculorum–Associated Oculocutaneous Rosacea in a Girl Successfully Treated With Ivermectin

Abstract: The causative role of Demodex folliculorum should be considered in immunocompetent children with rosacea or rosacea-like refractory eruptions. In such cases, treatment with ivermectin can be beneficial.

Cited by 44 publications

References 9 publications

Blepharitis and Demodex spp. infection

Blepharitis and Demodex spp. infection

A Case of Demodex folliculorum Associated with Blepharitis

Study of Demodex mites: Challenges and Solutions

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