Severe hypotension following spinal anesthesia in patients on amlodipine

Parida, Satyen; Nawaz, Mohammad; Kundra, Pankaj

doi:10.4103/0970-9185.98373

Cited by 4 publications

(5 citation statements)

References 2 publications

(2 reference statements)

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“…We used 15 mL/kg of Ringer's lactate to reason out hypotension was mainly the effect of vasodilatation after spinal and precipitated effect of antihypertensives and not due to absence of coloading. Parida S. 10 described in case series regarding the severity of Hypotension following spinal anaesthesia in patients on amlodipine 10 mg even after withholding morning dose and preloading before spinal, our study correlated with the findings of the series but degree of hypotension was less probably because study group involved young patients also where the vasomotor tone is preserved compared to older individuals. 11 Structural changes (Medial hyperplasia and hypertrophy) in arteriolar walls play a primary role in haemodynamic response to anaesthesia and explain greater changes in systemic vascular resistance and arterial pressure in hypertensive patients than normotensive patients with similar degree of sympathetic blockade.…”

Section: Discussionsupporting

confidence: 79%

Comparison of Haemodynamic Profile After Spinal Anaesthesia in Patients on Regular Treatment With Calcium Channel Blockers and Β Blockers

Kavyashree¹,

Patel²,

Girish³

et al. 2016

jemds

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BACKGROUNDHypertensive patients develop wide swings in blood pressure intraoperatively, especially after spinal anaesthesia. Long term antihypertensive agents can modify this effect by controlling blood pressure. This study was undertaken to evaluate the haemodynamic effect in hypertensive patients on regular treatment with calcium channel blockers and beta-blockers who are undergoing elective surgery under spinal anaesthesia and compared with normotensives.

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Section: Discussionsupporting

confidence: 79%

Comparison of Haemodynamic Profile After Spinal Anaesthesia in Patients on Regular Treatment With Calcium Channel Blockers and Β Blockers

Kavyashree¹,

Patel²,

Girish³

et al. 2016

jemds

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“…However, some authors have reported incidences of severe postoperative hypotension with use of amlodipine, a commonly prescribed calcium channel blocker antihypertensive agent. [ 11 12 ] In this study, amlodipine was omitted on the morning of surgery to prevent its undesirable hypotensive effect.…”

Section: Discussionmentioning

confidence: 99%

Outcome of anesthesia in elective surgical patients with comorbidities

et al. 2016

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Background:Presence of comorbidity in surgical patients may be associated with adverse perioperative events and increased the risk of morbidity and mortality. This audit was conducted to determine the frequencies of comorbidities in elective surgical patients and the outcome of anesthesia in a Tertiary Hospital in Nigeria.Materials and Methods:Observational study of a cross-section of adult patients scheduled for elective surgery over a 6-month period. A standardized questionnaire was used to document patients’ demographics, the presence of comorbidity and type, surgical diagnosis, anesthetic technique, intraoperative adverse events, and outcome of anesthesia. The questionnaire was administered pre- and post-operatively to determine the effects of the comorbidities on the outcome of anesthesia.Results:One hundred and sixty-five adult patients aged between 18 and 84 years were studied. There were 89 (53.9%) females and 76 (46.1%) males. Forty-five (27.3%) have at least one comorbidity. Hypertension was the most common (48.8%) associated illness. Other comorbidities identified include anemia (17.8%), asthma (8.9%), diabetes mellitus (6.7%), chronic renal disease (6.7%), and others. The perioperative period was uneventful in majority of patients (80.6%) despite the presence of comorbidities. Intraoperative adverse events include hypotension, hypertension, shivering, and vomiting. No mortality was reported.Conclusion:Hypertension was the most common comorbidity in this cohort of patients. The presence of comorbidity did not significantly affect the outcome of anesthesia in elective surgical patients.

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“…In the course of anaesthetic management of patients with hypertension, the continuation of antihypertensive medication throughout the preoperative period was done to reduce the risk of uncontrolled hypertension still in 5 (9.8%) cases with comorbidities hypertension was observed preoperatively .Some authors have reported severe postoperative hypotension with use of amlodipine. [18] Due to increase in the prevalence of hypertension in our area patients with comorbidities as diabetes was high in our study.…”

Section: Discussionmentioning

confidence: 73%

Anaesthesia in Elective Surgery and its Outcome

Khot

Verma

2018

ijirms

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INTRODUCTION Anaesthesia is classified into two main techniques general anaesthesia (GA) in which gaseous and/or intravenous drugs achieve central neurological depression, and regional anaesthesia, in which drugs are administered directly to the vicinity of spinal cord or nerves to locally block afferent and efferent nerves. The anaesthesiologist is the medical specialists who can evaluate the risk associated with the anaesthesia discuss these risks with the patient and surgeon to manage them intraoperative. Now a day anesthesia is no longer limited to the operation room but it a perioperative care . The presence of comorbid conditions in surgical patients is significant factors in preoperative morbidity and mortality risk assessment . The current practices in anesthesia include complete valuation of risks, control costs, allocate resources, and postpone surgery until interventions improve risk .

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Severe hypotension following spinal anesthesia in patients on amlodipine

Cited by 4 publications

References 2 publications

Comparison of Haemodynamic Profile After Spinal Anaesthesia in Patients on Regular Treatment With Calcium Channel Blockers and Β Blockers

Comparison of Haemodynamic Profile After Spinal Anaesthesia in Patients on Regular Treatment With Calcium Channel Blockers and Β Blockers

Outcome of anesthesia in elective surgical patients with comorbidities

Anaesthesia in Elective Surgery and its Outcome

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