Severe hypokalaemic paralysis from an unusual cause mimicking the Guillain-Barr� syndrome

Valtier, B.; Mion, G.; Pham, Lan; Brochard, Laurent

doi:10.1007/bf00273568

Cited by 14 publications

(11 citation statements)

References 5 publications

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“…Potassium depletion is probably due to renal potassium wasting as a consequence of renal damage, osmotic diuresis and gut loss through intestinal secretion. When the potassium deletion is severe, the patient may develop a flaccid paralysis [7,8]. Resulting quadriparesis may be mistaken for GuillainBarre syndrome [7], as happened in the present case.…”

Section: Discussionmentioning

confidence: 79%

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Life threatening hypokalemia and quadriparesis in a patient with ureterosigmoidostomy

Rafique

2007

Int Urol Nephrol

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We report quadriparesis as a result of severe hypokalemia and acidosis in a 15-years-old young man who had undergone ureterosigmoidostomy for bladder extrophy 3 months earlier. The patient was initially mistakenly diagnosed to be a case of Guillain-Barre syndrome. On investigations acidosis and profound hypokalemia were present. Dramatic improvement occurred after correction of hypokalemia and acidosis with intravenous potassium and bicarbonate. The underlying mechanism as well as the treatment of hyperchloremic metabolic acidosis and hypokalemia after ureterosigmoidostomy are hereby discussed.

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Section: Discussionmentioning

confidence: 79%

“…When the potassium deletion is severe, the patient may develop a flaccid paralysis [7,8]. Resulting quadriparesis may be mistaken for GuillainBarre syndrome [7], as happened in the present case.…”

Section: Discussionmentioning

confidence: 79%

Life threatening hypokalemia and quadriparesis in a patient with ureterosigmoidostomy

Rafique

2007

Int Urol Nephrol

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“…Bu durum kas güçsüzlüğü ile klinik belirti verir. Literatürde üreterosigmoidostomi sonrası, genel kas güçsüzlüğü ile başvuran hastalarda Guillain-Barre sendromu ile karştırıldığı olgular rapor edilmiştir (9,10,11). Üriner diversiyonlar için jejunum kullanıldığında oluşan elektrolit bozuklukları, özellikle proksimal jejunum kullanıldığında, hiponatremi, hipokloremi, azotemi ve asidozla sonuçlanır.…”

Section: Elektrolit Ve Asit-baz Değişiklikleriunclassified

Metabolic Changes Developing During Urinary Intestinal Diversion after Radical Cystectomy

Erdem¹,

Şengör²

2015

uob

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“…It can result with general weakness and arrhythmias. It can create diagnostic problems and can be taken for Guillain-Barre resembling syndrome [33].…”

Section: Acid-base and Ions Imbalancementioning

confidence: 99%

Urinary Diversion Metabolic Complications – Underestimated Problem

Krajewski¹,

Piszczek²,

Krajewska³

et al. 2014

Adv Clin Exp Med

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Bladder cancer is one of the most frequent human cancers. In 2011 more than six thousand people in Poland developed BC and more than three thousand died because of it. Treatment of bladder cancer depends on its stage. In less advanced tumours (Ta, Tcis, T1) transurethral resection of bladder tumor with adjuvant immunotherapy is often therapeutic. In more advanced cases (≥ T2) radical cystectomy is needed. There are several surgical types of postcystectomy urinary diversion divided into two fundamental types -enabling and not enabling urine continence. The most common procedures include ureterocutaneostomy, ileal or colon conduit, orthopic ileal bladder, heterotopic continent bladder replacement (pouch) and urinary diversion via the rectum. Depending on type of cystectomy, various metabolic complications occur, because the absorptive-secretory function of used bowel segment is intact. Complications include bowel dysfunction, malabsorption of various vitamins, acid-base imbalance, electrolyte imbalance, abnormalities in bone metabolism, formation of renal calculi, secondary malignancies and disturbances in function of kidneys or liver. Early diagnosed complications can be treated easier, recognised in advanced stages are often irreversible. In our paper we present review of different approaches to bladder cancer treatment and metabolic complications occurring after these procedures (Adv Clin Exp Med 2014, 23, 4, 633-638). Bladder cancer (BC) is one of the most frequent human cancers. In 2011 more than six thousand people in Poland developed BC and more than three thousand died because of it. In terms of morbidity in 2011 it was the fifth in male and fifteenth in female cancer in Poland [1]. Frequently, the sole symptom of BC is microscopic or macroscopic haematuria, without any pain or urinary disorders. Other possible symptoms like polyuria or urinary urgency can indicate carcinoma in situ. However, palpable tumor in abdomen, bone pain or weight loss can identify advanced and metastatic cancer.Incidence and prevalence of BC increase with age and exposure to environmental toxins like cigarette smoke. It is proven that smokers have 2 to 6 times grater chance of BC development [2]. Male gender, inflammation, chronic infection of bladder and previous radiotherapy are other predisposing factors.The most common histological type of BC is urothelial cancer. Staging of BC is based on invasion of bladder wall, and is described within TNM (tumor, nodes, metastases) system. Treatment of BC depends on its stage. From a clinical point of view, the most important division is one, which splits into noninfiltrating lamina muscularis tumours (Ta, Tcis, T1) and those infiltrating lamina muscularis (≥ T2). In the first group the procedure of choice is TURB (transurethral resection of bladder tumor), which is diagnostic and often therapeutic. If TURB procedure is insufficient, according to staging and clinical situation, re-TURB or adjuvant immunotherapy can be introduced. In tumours with muscular invasion the method of choi...

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Severe hypokalaemic paralysis from an unusual cause mimicking the Guillain-Barr� syndrome

Cited by 14 publications

References 5 publications

Life threatening hypokalemia and quadriparesis in a patient with ureterosigmoidostomy

Life threatening hypokalemia and quadriparesis in a patient with ureterosigmoidostomy

Metabolic Changes Developing During Urinary Intestinal Diversion after Radical Cystectomy

Urinary Diversion Metabolic Complications – Underestimated Problem

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