Severe gastrointestinal involvements in patients with adult dermatomyositis with anti-NXP2 antibody
Yakai Fu,
Liyang Gu,
Jie Chen
et al.
Abstract:ObjectiveGastrointestinal (GI) involvements were scarcely reported in adult anti-nuclear matrix protein 2 (NXP2) dermatomyositis (NXP2+DM). In this study, we investigated the clinical, pathological and molecular features as well as treatment options of this rare yet life-threatening disease.MethodsWe retrospectively collected the data of the cohort of NXP2+DM from 2012 to 2022 in our hospital. RNA sequencing was performed in intestinal samples of perforated patients compared with healthy controls data set.Resu… Show more
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