Severe form of encephalopathy associated with 2009 pandemic influenza A (H1N1) in Japan

Okumura, Akihisa; Nakagawa, Satoshi; Kawashima, Hisashi; Morıchı, Shinichiro; Muguruma, Takashi; Saito, Osamu; Fujimoto, Junichi; Toida, Chiaki; Kuga, Shuji; Imamura, Toshihiro; Shimizu, Toshiaki; Kondo, Naomi; Morishima, Tsuneo

doi:10.1016/j.jcv.2012.10.007

Cited by 25 publications

(12 citation statements)

References 41 publications

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“…The infections with C. neoformans spar a varied clinical spectrum in immunocompromised host, from meningitis, pneumonia, soft tissue and bone infections. [ 6 7 ] Pandemic influenza is also a major cause of morbidity and mortality in HIV-infected individuals, and also in patients undergoing treatment with highly active antiretroviral therapy. The meningeal signs and symptoms have also been attributed to pandemic influenza in a small number of cases.…”

Section: Discussionmentioning

confidence: 99%

Concomitant Infections of Influenza A H1N1 and Disseminated Cryptococcosis in an HIV Seropositive Patient

et al. 2015

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Section: Discussionmentioning

confidence: 99%

Concomitant Infections of Influenza A H1N1 and Disseminated Cryptococcosis in an HIV Seropositive Patient

et al. 2015

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“…Respecto al pronóstico de esta patología, suele ser variable y depende del estado inmunitario del paciente así como de las distintas complicaciones asociadas 6,7 .…”

Section: Discussionunclassified

Encefalitis vírica y convulsiones refractarias por gripe A en época no estacional

Cebrián

Morell

Centelles

et al. 2015

Rev Pediatr Aten Primaria

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Influenza A viral encephalitis and refractory seizures out of season El virus H1N1 se caracteriza por producir sobretodo sintomatología respiratoria y presentarse en época invernal o epidemiológica. Presentamos el caso de una paciente que debutó con cuadros convulsivos en mayo, fuera de la poca invernal y requirió cuidados intensivos. The H1N1 virus is characterized by producing respiratory symptoms mostly in winter or epidemiological time. We report the case of a patient that started with seizures in May, out of the winter, and required intensive care.

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“…Amongst eight patients with H1N1 encephalopathy reported by Fuchigami et al, four had SE [ 9 ]. Okumura et al reported that four of his twenty children with H1N1 encephalopathy had SE, but the seizures were “treated successfully with intravenous antiepileptic drugs” [ 10 ]. Other studies reported on single cases of SE in children or adolescents with good recovery [ 4 , 7 , 11 ].…”

Section: Discussionmentioning

confidence: 99%

New Onset Refractory Status Epilepticus in a Young Man with H1N1 Infection

Ibrahim

Haddad

2014

Case Reports in Neurological Medicine

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Objective. To report a case of refractory status epilepticus (SE) as an unusual early manifestation of H1N1 influenza infection. Introduction. H1N1 neurological complications have been reported and consist mainly of seizures or encephalopathy occurring in children. However, we only found a single report of an adult developing complex partial SE with H1N1 infection. Case Report. A 21-year-old previously healthy man was brought to the emergency room (ER) after a witnessed generalized tonic clonic seizure (GTCS). He was fully alert and afebrile upon ER arrival, but a second GTCS prompted treatment with Lorazepam and Fosphenytoin. The initial EEG showed diffuse slowing, but a repeat one requested as the patient failed to regain consciousness revealed recurrent focal seizures of independent bihemispheric origin, fulfilling the criteria for nonconvulsive SE. Chest X-ray, followed by chest CT scan, showed a left upper lobe consolidation. H1N1 infection was confirmed with PCR on bronchoalveolar lavage material. Despite aggressive treatment with Midazolam, Propofol, and multiple high dose antiepileptic drugs, the electrographic seizures recurred at every attempt to reduce the intravenous sedative drugs. The patient died two weeks after his initial presentation. Conclusion. H1N1 should be added to the list of rare causes of refractory SE, regardless of the patient's age.

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Severe form of encephalopathy associated with 2009 pandemic influenza A (H1N1) in Japan

Cited by 25 publications

References 41 publications

Concomitant Infections of Influenza A H1N1 and Disseminated Cryptococcosis in an HIV Seropositive Patient

Concomitant Infections of Influenza A H1N1 and Disseminated Cryptococcosis in an HIV Seropositive Patient

Encefalitis vírica y convulsiones refractarias por gripe A en época no estacional

New Onset Refractory Status Epilepticus in a Young Man with H1N1 Infection

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