Abstract:Introduction. Darier's disease is a rare genodermatosis inherited in an autosomal dominant manner. Clinically, it manifests with hyperkeratotic papules in seborrhoeic and intertriginous areas as well as involvement of nail plates and mucous membranes. Patients may present with neuropsychiatric comorbidities. Objective. To present a case of a patient with severe Darier's disease that was successfully treated with acitretin. Case report. A 39-year-old man with a 24 year history of Darier's disease was admitted t… Show more
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