Severe cervical glandular cell lesions and severe cervical combined lesions

Abstract

On the basis of a data search of the PALGA registry, it can be concluded that in a relatively large number of cases a severe cervical glandular cell lesion was not diagnosed on the Pap smear. Furthermore, data demonstrated that the prediction of a glandular abnormality is less accurate in cases of combined squamoglandular cell lesions than in pure glandular cell lesions.

Histological Correlation of Glandular Abnormalities in Cervical Liquid-Based Cytology

“…Also, the detection rate of all the positive cases by either CS or TP was similar to that reported previously [20, 21, 24]. In nine cases analyses, in which AGC or adenocarcinoma were considered by histological examination or HPV infection status, screening as the abnormality to be AGC or more was possible in nine cases by CS and in six cases by TP; thus, CS method seems to be better in the point of accuracy for screening.…”

Abstracts of proffered papers and posters. Joint BSCC‐NAC ASM, Keele, 13–16 July 2011

“…3,9,10 This co-existence is a likely confounding variable affecting the predictive value of the ?Glandular Neoplasia report. 4,13,14 Objective: Abstract: Fine needle aspiration cytology is still commonly used in the first line pathological investigation of breast diseases. The National Health Service Breast Screening Programme (NHSBSP) has guidelines with five reporting categories (C1-C5) for these cases, with C3 (equivocal/atypia probably benign) and C4 (suspicious of malignancy) as categories of uncertainty that may be helpful in difficult cases.…”

Nomenclatura Brasileira para Laudos Cervicais e Condutas Preconizadas: recomendações para profissionais de saúde

“…A repetição do exame citopatológico possui sensibilidade entre 67% e 85% (28)(29)(30)(31)(32)(33)(34) . Não existem dados suficientes para definir o número e o intervalo entre as repetições das citologias, sendo definido pelo grupo de trabalho o intervalo de seis meses.…”

“…Cerca de 48% a 69% das mulheres com laudo citopatológico sugestivo de adenocarcinoma in situ apresentam u confirmação da lesão à histopatologia e, dessas, 38% apresentam laudo de adenocarcinoma invasor (17,31) . Portanto, todas as pacientes com citologia sugestiva de adenocarcinoma in situ, encontrada na unidade de atenção básica, deverão ser encaminhadas para a unidade de referência de média complexidade para colposcopia imediata, assim como as portadoras de laudo citopatológico sugestivo de adenocarcinoma invasor.…”