“…The trials compared hibiscus with another tea beverage, a placebo, or a prescribed diet Of the studies, 10 administered hibiscus as a capsule and 7 as a tea beverage. Doses of hibiscus ranged from 15 mg to 9 g/day, and duration of studies ranged from 15 to 90 days Liver damage, hepatitis (Vasques et al, 2008) In a trial involving 60 overweight Brazilian women, randomised into two groups (2400 mg/day of Garcinia gummi-gutta (L.) N.Robson or placebo) for 60 days, liver transaminase analysis and creatinine clearance showed no signs of acute toxicity during treatment; gastric discomfort, increased evacuation and nausea were reported as adverse effects (Vasques et al, 2014) (Actis et al, 2007;Shim and Saab, 2009;Fong et al, 2010;Sharma et al, 2010;Shuster, 2010;Araujo and Worman, 2015;Mancano, 2015;Melendez-Rosado et al, 2015;Corey et al, 2016;Lunsford et al, Case reports, case series More than 20 cases related to the use of dietary supplement containing Garcinia gummi-gutta (L.) N.Robson describreported the development of acute liver injury or hepatic necrosis as the final event in several case series (Steven et al, 2005;Actis et al, 2007;Dara et al, 2008;US FDA, 2009;Shuster et al, 2010 ;Sharma et al, 2010 ;Arujado et al 2015 ;Mancano et al, 2015;Melendez-Rosado et al 2015;Kothadia et al, 2016;Smith et al 2016 ;Smith et al, 2016;Crescioli et al, 2018;Kothadia et al, 2018;Philips and Augustine, 2018;Sharma et al, 2018;Yousaf et al, 2019;Ferreira et al, 2020;Khetpal et al, 2020;ANSES, 2022;…”