Severe Anaerobic Necrotizing Pneumonia Complicated by Pyopneumothorax and Anaerobic Monoarthritis Due to &lt;i&gt;Peptostreptococcus magnus&lt;/i&gt;

Panagou, Panagiotis; Papandreou, L.; Bouros, D

doi:10.1159/000195932

Cited by 12 publications

(12 citation statements)

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“…Dierentiation of lung abscess from NP may have therapeutic implications, particularly for cases in whom percutaneous drainage of the lung abscesses are considered. With the advent of CT scans since the 1980s, NP has been encountered more frequently [6,11,12,20,24,30,32], however, the clinical signi®cance of NP has not been fully investigated. The unfamiliarity and newly recognised radiological features of NP sometimes generate more anxiety to the physicians that could lead to prolonged hospitalisation or even unnecessary surgical interventions.…”

Section: Discussionmentioning

confidence: 99%

Necrotising pneumonitis in children

et al. 2000

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The clinical course of necrotising pneumonitis in children following complicated pneumonia is often prolonged despite adequate antibiotic therapy. Necrotising pneumonitis with co-existing multiple loculations, pneumothorax/ bronchopleural fistula in the empyema and extensive pleural peel are poor prognostic factors for medical therapy. Thoracoscopic removal of loculated empyema, lysis of adhesions and/or decortication are effective in relieving tachypnoea, chest pain, and controlling fever and improve the outcome, especially in children with empyema.

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Section: Discussionmentioning

confidence: 99%

Necrotising pneumonitis in children

et al. 2000

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“…Most infections involving GPAC are polymicrobial (35,90), particularly abscesses and those developing from mucocutaneous surfaces. However, there are many instances of their isolation in pure culture; most relate to P. magnus (14,32,38,51,64,72,77,94,141,173,196,207,214,217,231), but there are also reports of P. anaerobius (181), P. asaccharolyticus (196), P. indolicus (13), P. micros (210,278), P. vaginalis (189,196), and "P. harei" (188).…”

Section: Clinical Importancementioning

confidence: 99%

“…Several factors, including the age of the patient and the cause of the empyema, could account for these differences; further reports would be valuable. P. magnus has been isolated in pure culture from a patient with necrotizing pneumonia (207).…”

Section: Oral and Respiratory Tract Infectionsmentioning

confidence: 99%

Gram-Positive Anaerobic Cocci

1998

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SUMMARY Gram-positive anaerobic cocci (GPAC) are a heterogeneous group of organisms defined by their morphological appearance and their inability to grow in the presence of oxygen; most clinical isolates are identified to species in the genus Peptostreptococcus. GPAC are part of the normal flora of all mucocutaneous surfaces and are often isolated from infections such as deep organ abscesses, obstetric and gynecological sepsis, and intraoral infections. They have been little studied for several reasons, which include an inadequate classification, difficulties with laboratory identification, and the mixed nature of the infections from which they are usually isolated. Nucleic acid studies indicate that the classification is in need of radical revision at the genus level. Several species of Peptostreptococcus have recently been described, but others still await formal recognition. Identification has been based on carbohydrate fermentation tests, but most GPAC are asaccharolytic and use the products of protein degradation for their metabolism; the introduction of commercially available preformed enzyme kits affords a physiologically more appropriate method of identification, which is simple and relatively rapid and can be used in routine diagnostic laboratories. Recent reports have documented the isolation in pure culture of several species, notably Peptostreptococcus magnus, from serious infections. Studies of P. magnus have elucidated several virulence factors which correlate with the site of infection, and reveal some similarities to Staphylococcus aureus. P. micros is a strongly proteolytic species; it is increasingly recognized as an important pathogen in intraoral infections, particularly periodontitis, and mixed anaerobic deep-organ abscesses. Comparison of antibiotic susceptibility patterns reveals major differences between species. Penicillins are the antibiotics of choice, although some strains of P. anaerobius show broad-spectrum β-lactam resistance.

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“…Firstly, necrotizing pneumonia usually occurs in patients with underlying risk factors, i.e. alcohol abuse, nutritional deficiency or malignancy, which render perioperative management difficult [5,6]. Secondly, the development of devastating complications, such as progressive diffuse pneumonia, septic shock and respiratory failure, increases the severity of the disease.…”

Section: Introductionmentioning

confidence: 99%

Surgical Treatment of 26 Patients with Necrotizing Pneumonia

Tsai¹,

Tsai²,

2011

Eur Surg Res

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Background: This study aimed to review the outcome of patients treated with surgical resection for necrotizing lung infection with various co-morbidities and complications. Methods: The records of 26 patients treated with pulmonary resection for necrotizing pneumonia between July 2004 and January 2010 were retrospectively reviewed. Surgical procedures included large wedge resection (n = 1), lobectomy (n = 19) and bilobectomy (n = 6). Results: The study cohort consisted of 21 men and 5 women aged 35–85 years (mean 64.7 ± 15.0 years). Twenty-three (88.5%) patients had underlying risk factors. At surgical consultation, 17 patients presented with progressive respiratory distress; 6 required ventilatory support; 12 had empyema, and in 5 patients the conditions were complicated by bronchopleural fistula. Four patients had septic shock requiring vasopressor support. Three patients developed hemoptysis. Two patients had bilateral diffuse pneumonia. Klebsiella pneumoniaeand Streptococcusviridans were the most common pathogens. The right lower (n = 13) and right middle lobes (n = 10) were the most frequently affected. Four deaths (15.4%) occurred: 3 due to perioperative progressing pulmonary infection/inflammation and 1 due to hepatorenal failure. Postoperative empyema occurred in 3 patients. One patient became ventilator dependent. Conclusion: Pulmonaryresection for necrotizing pneumonia is a feasible treatment option in patients with progressive pulmonary sepsis.

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Severe Anaerobic Necrotizing Pneumonia Complicated by Pyopneumothorax and Anaerobic Monoarthritis Due to <i>Peptostreptococcus magnus</i>

Cited by 12 publications

References 1 publication

Necrotising pneumonitis in children

Necrotising pneumonitis in children

Gram-Positive Anaerobic Cocci

Surgical Treatment of 26 Patients with Necrotizing Pneumonia

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