Severe acute pancreatitis in the elderly: Etiology and clinical characteristics

Xin, Ming-jun; Hong, Chen; Luo, Bin; Sun, Jiayi

doi:10.3748/wjg.14.2517

Cited by 58 publications

(59 citation statements)

References 27 publications

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“…Gallstone frequency increases with age, so gallstones should be suspected whenever acute pancreatitis occurs in elderly subjects [19]. In any age group, careful examination may disclose that some cases of "idiopathic" pancreatitis are in fact caused by tiny gallstones [20].…”

Section: Gallstonesmentioning

confidence: 99%

The changing character of acute pancreatitis: Epidemiology, etiology, and prognosis

Lowenfels

Maisonneuve²,

Sullivan³

2009

Curr Gastroenterol Rep

186

109

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Acute pancreatitis continues to be a diagnostic and therapeutic challenge for physicians and surgeons. It ranks third in the list of hospital discharges for gastro-intestinal diseases. In most patients the cause is either gallstones or alcoholism. The overall mortality is less than 5%, but severe acute pancreatitis leads to prolonged hospitalization and much higher mortality. There are important differences in disease susceptibility and case fatality rates: the incidence is higher in blacks than in whites, and mortality is higher in older patients than in younger patients. Reports from various countries reveal that the frequency of acute pancreatitis is increasing, perhaps in relation to rising obesity rates, which would increase the likelihood of gallstone pancreatitis. Conversely, mortality rates for acute pancreatitis are declining in many, but not all, reports.

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Section: Gallstonesmentioning

confidence: 99%

The changing character of acute pancreatitis: Epidemiology, etiology, and prognosis

Lowenfels

Maisonneuve²,

Sullivan³

2009

Curr Gastroenterol Rep

186

109

View full text Add to dashboard Cite

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“…Gallstones and alcohol together are the two major etiological factors for AP more than 80% (20,21). In elderly patients, the biliary and idiopathic pancreatitis are reported as 64.9% and 26.6% respectively (22). Many studies have indicated a worse prognosis in idiopathic AP compared to pancreatitis induced by alcoholism or gallstone (23).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of CT severity index, Ranson and APACHE II and Ranson scores for clinical course and mortality in mechanically ventilated patients depend to severe pancreatitis

Adam¹,

Koçak²,

Çınar³

et al. 2017

Van Med J

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Objective:To evaluate the utility of CT severity index (CTSI) and two main scoring systems (Ranson and APACHE II) for patients underwent mechanical ventilation due to pulmonary complications associated with severe pancreatitis. Materials and Methods:Mechanical ventilated patients due to severe acute pancreatitis were enrolled the study. CTSI and two traditional clinical scoring systems including APACHE II and Ranson were used to predict the mortality rates in mechanical ventilated patients due to severe AP. Results:Nine of 36 patients were survived (25%). The ICU (Intensive Care Unit) mortality was 66.6% (n= 24) and hospital mortality was 75% (n=27). Patients had upper then 17 scores for APACHE II score, the sensitivity and specificity were 64% and 66%, respectively to predict the mortality, by CTSI (>4) and Ranson scoring system (>6) with sensitivity and specificity of 60% and 40% and 50% and 46%, respectively. Conclusion:In this study, high scores of CTSI, Ranson and APACHE II were found to be independent predictors in patients underwent mechanical ventilated due to severe pancreatitis in ICU. However, APACHE II was the most reliable and effective scoring system for predicting the mortality rate.Key Words: Acute pancreatitis, APACHE II, CT severity index, Ranson scoring system ÖZET Amaç:Şiddetli akut pankreatitte, pulmoner komplikasyonlar sıklıkla görülmektedir. Bu çalışmada, akut pankreatite bağlı gelişen pulmoner komplikasyonlar nedeniyle mekanik ventilasyon uygulanan hastalarda bilgisayarlı tomografi şiddet indeksi (CTSI) ve geleneksel iki farklı skorlama sistemi olan APACHE II ve Ranson skorlama sistemlerinin uygulanabilirliği ve güvenilirliğinin karşılaştırılması amaçlandı. Gereç ve

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“…The mortality of the aged was correlated with the severity of acute pancreatitis, multiple comorbidity, and incidence of multiple organ dysfunction syndrome. Multiple organ dysfunction syndrome was the main cause of death 91 . Focal to the diffuse enlargement of the pancreas, hypoechoic texture, and irregular borders are noted from ES in the elderly with acute pancreatitis.…”

Section: Es Assessments Of the Abdominal System In The Elderlymentioning

confidence: 99%