Severe acute pancreatitis

Young, S M; Thompson, Jonathan P.

doi:10.1093/bjaceaccp/mkn020

Cited by 7 publications

(4 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Hyperlipoproteinaemias types are recognized causes of up to 7% of all pancreatitis cases. 1,2 In our patient, with no recent history of alcohol consumption, high triglycerides remain the likely cause of the pancreatitis. There is some evidence that cholestasis and biliary obstruction may be contributing to the hypertriglyceridaemia as well.…”

Section: Discussionmentioning

confidence: 60%

See 1 more Smart Citation

Lipoprotein X in a patient with cholestasis and hypertriglyceridaemia

et al. 2013

View full text Add to dashboard Cite

Hypertriglyceridaemia is an established cause of acute pancreatitis and responds to insulin therapy in addition to lipid lowering medication. We report a case of severe hypertriglycaeridemia of 149 mmol/L in a 36-year-old man with type 2 diabetes who presented to the surgical ward with abdominal pain due to pancreatitis and developed acute cholestasis, jaundice and eruptive xanthomata. His triglycerides improved to 3.8 mmol/L with sliding scale insulin within two weeks of in-hospital stay. However, his total cholesterol remained raised at 23.7 mmol/L. The lipoprotein electrophoresis confirmed the presence of lipoprotein X associated with bile obstruction, which contributed to an increase in total cholesterol. The total cholesterol normalized on improvement of his cholestasis. 2013; 50: 173-175. DOI: 10.1258 50: 173-175. DOI: 10. /acb.2012 Case A 36-year-old Caucasian man was admitted to the surgical ward in this hospital with the third episode of acute on chronic pancreatitis in the previous six years. Two earlier such events were followed by recurrent complex pancreatic surgery. He also had a cholecystectomy performed for gallstones. The patient had an eight-year history of type 2 diabetes, poorly controlled by treatment with metformin and insulin (glycosylated haemoglobin [HbA1c] 12.5%, 113 mmol/mol) and a history of non-alcoholic steatohepatitis. Prior to the admission in order to control his lipid profile he had been on atorvastatin tablets for months but had run out of his medications and was off them for approximately eight weeks. He has never smoked and ceased drinking alcohol after the first episode of pancreatitis in 2005. His past history included self-administration of steroid and testosterone injections in the year 2000 for building muscle strength before participating in heavy-lifting competitions. Ann Clin Biochem

show abstract

Section: Discussionmentioning

confidence: 60%

“…1,3 Steroids, like many other drugs, have been documented to cause acute pancreatitis. 2 However, in view of the steroid use for only a short period of time and long before the first episode of pancreatitis, it is unlikely to have been a potential cause of pancreatitis. The effect of anabolic steroids on triglycerides is well known.…”

Section: Discussionmentioning

confidence: 99%

Lipoprotein X in a patient with cholestasis and hypertriglyceridaemia

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Да је акут ни пан кре а ти тис био те жак здрав стве ни про блем још у ста ром ве ку све до чи и по да так да се смрт Алек сан дра Ве ли ког (356-323 п.н.е.) при пи су је акут ном не кро ти зу ју ћем пан кре а ти ти су иза зва ном обил ним уно сом хра не и ве ли ке ко ли чи не ал ко хо ла [1].…”

Section: уводunclassified

Comparison of biohumoral and morphological parameters in acute pancreatitis

Tasic¹,

Grgov²,

Nagorni

et al. 2014

Srp Arh Celok Lek

View full text Add to dashboard Cite

There was a negative correlation between the level of ionized calcium in the blood and the degree of the acute pancreatitis by the Balthazar score. Mean value of alpha amylase, total value of cholesterol and ALT were significantly higher in the group of biliary compared to the group of etilic acute pancreatitis. The average values of the alpha amylase, LDH and ALT were significantly higher in the group of severe form of the acute pancreatitis compared to the group of moderate form. The ratio AST/ALT was significantly higher in the group of etilic than in the group of biliary pancreatitis.

show abstract

“…published in Continuing Education in Anaesthesia, Critical Care & Pain a decade ago. 3 This article provides an update on the classification and evidence-based management of AP.…”

mentioning

confidence: 99%

Management of the patient with acute pancreatitis

2019

View full text Add to dashboard Cite

By reading this article you should be able to: Classify acute pancreatitis and list its common causes. Explain the principles of investigation and supportive management of patients with acute pancreatitis. Describe the local complications of acute pancreatitis and understand the indications and options for intervention. Discuss the potential long-term sequelae after acute pancreatitis and strategies to prevent its recurrence. Acute pancreatitis (AP) is an acute inflammatory disorder of the pancreas. It is a leading cause of hospital admission for gastrointestinal (GI) disorders and the incidence is rising. 1 Although the vast majority of patients have a self-limiting illness, those with severe AP account for 2.4% of ICU beds occupied in England and Wales, and have an in-hospital mortality of 40%. 2 A previous article on severe AP was Matrix codes: 1A02,

show abstract

Severe acute pancreatitis

Cited by 7 publications

References 13 publications

Lipoprotein X in a patient with cholestasis and hypertriglyceridaemia

Lipoprotein X in a patient with cholestasis and hypertriglyceridaemia

Comparison of biohumoral and morphological parameters in acute pancreatitis

Management of the patient with acute pancreatitis

Contact Info

Product

Resources

About