Severe acute malnutrition and infection

Jones, Kelsey; Berkley, James A.

doi:10.1179/2046904714z.000000000218

Cited by 120 publications

(125 citation statements)

References 187 publications

(193 reference statements)

Supporting

Mentioning

116

Contrasting

Unclassified

Order By: Relevance

“…Some authors have also reported that vitamin A and iron deficiencies increased the risk of death among HIV-infected patients [14]. Nevertheless, the impact of malnutrition on the alteration of immune mechanisms remains insufficiently investigated [11,15].…”

Section: Hiv Infection and Malnutrition In Children: A Vicious Circlementioning

confidence: 97%

Challenges of malnutrition care among HIV-infected children on antiretroviral treatment in Africa

Jesson

Leroy

2015

Médecine et Maladies Infectieuses

View full text Add to dashboard Cite

Section: Hiv Infection and Malnutrition In Children: A Vicious Circlementioning

confidence: 97%

Challenges of malnutrition care among HIV-infected children on antiretroviral treatment in Africa

Jesson

Leroy

2015

Médecine et Maladies Infectieuses

View full text Add to dashboard Cite

“…Iatrogenic infections result from a combination of these factors. Malnutrition in some ways mimics intestinal failure and has been shown to account for severe infections (38). The various types of organ failure associated with malnutrition may contribute to immunodeficiency (39).…”

Section: Acquired Immunodeficiencymentioning

confidence: 99%

Human genetic basis of interindividual variability in the course of infection

Casanova

2015

Proc. Natl. Acad. Sci. U.S.A.

156

111

View full text Add to dashboard Cite

The key problem in human infectious diseases was posed at the turn of the 20th century: their pathogenesis. For almost any given virus, bacterium, fungus, or parasite, life-threatening clinical disease develops in only a small minority of infected individuals. Solving this infection enigma is important clinically, for diagnosis, prognosis, prevention, and treatment. Some microbes will inevitably remain refractory to, or escape vaccination, or chemotherapy, or both. The solution also is important biologically, because the emergence and evolution of eukaryotes alongside more rapidly evolving prokaryotes, archaea, and viruses posed immunological challenges of an ecological and evolutionary nature. We need to study these challenges in natural, as opposed to experimental, conditions, and also at the molecular and cellular levels. According to the human genetic theory of infectious diseases, inborn variants underlie life-threatening infectious diseases. Here I review the history of the field of human genetics of infectious diseases from the turn of the 19th century to the second half of the 20th century. This paper thus sets the scene, providing the background information required to understand and appreciate the more recently described monogenic forms of resistance or predisposition to specific infections discussed in a second paper in this issue.

show abstract

“…Preschool children have been specifically studied because their health status is a sensitive indicator of overall community health, particularly among disadvantaged groups in populations [28,29]. This group is also nutritionally vulnerable due to their easy susceptibility to undernutrition and infection [30,31]. They require a high supply of nutrients since they are usually very active and their growth rate is rapid.…”

Section: Introductionmentioning

confidence: 99%

Maternal Body Mass Index Is Strongly Associated with Children Z-Scores for Height and BMI

Tigga

Sen

2016

Journal of Anthropology

View full text Add to dashboard Cite

Introduction. Undernutrition continues to be a major public health problem throughout the developing world, particularly in subSaharan Africa and Asia including India. Limited studies suggest associations between maternal body mass index (BMI) and child nutritional status. The present study aims to determine the relationship between maternal BMI and children nutritional status. Methods. The study was conducted among 246 mothers who had given birth to single children ( = 246) and belonged to the Proto-Australoid population of North Bengal, India. The anthropometric measurements of height and weight were recorded following standard procedures. Overall body composition was evaluated using BMI. Result. The results showed that overall mean BMI among mothers was 20.63 ± 2.53 kg/m 2 , while those among boys and girls were 15.19 ± 1.62 kg/m 2 and 14.86 ± 1.37 kg/m 2 ( < 0.001), respectively. The BMI of mothers were significantly and highly correlated with HAZ (0.709) and BMIZ (0.748) ( < 0.001) of children. These are indicative of a strong genetic component between maternal and child anthropometry. Conclusion.The results indicate significant associations between mothers' and children's nutritional status. Assessments of body composition and nutritional status using BMI, especially among mothers and their children, are recommended.

show abstract

Severe acute malnutrition and infection

Cited by 120 publications

References 187 publications

Challenges of malnutrition care among HIV-infected children on antiretroviral treatment in Africa

Challenges of malnutrition care among HIV-infected children on antiretroviral treatment in Africa

Human genetic basis of interindividual variability in the course of infection

Maternal Body Mass Index Is Strongly Associated with Children Z-Scores for Height and BMI

Contact Info

Product

Resources

About