2020
DOI: 10.3389/fendo.2020.00346
|View full text |Cite
|
Sign up to set email alerts
|

Seven Years of Vitrified Blastocyst Transfers: Comparison of 3 Preparation Protocols at a Single ART Center

Abstract: Introduction: Frozen-thawed embryo transfers (FET) have become a standard practice to increase cumulative pregnancy rates, however, the choice of the best preparation protocol remains a matter of debate. Design: Retrospective analysis of clinical pregnancy (CPR) and live birth rate (LBR) of FET in natural cycles (NC-FET), modified natural cycles with hCG-triggered ovulation (mNC-FET), and hormonal artificial replacement (AR-FET). Materials and Methods: For natural cycles, patients were monitored by ultrasound … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

0
14
0

Year Published

2021
2021
2024
2024

Publication Types

Select...
8

Relationship

0
8

Authors

Journals

citations
Cited by 26 publications
(14 citation statements)
references
References 43 publications
(39 reference statements)
0
14
0
Order By: Relevance
“…Previous studies have reported that the early pregnancy loss rate in FET was higher when using the AC protocol compared to NC or SC ( Veleva et al , 2008 ; Tomás et al , 2012 ; Cerrillo et al , 2017 ; Peigné et al , 2019 ; Liu et al , 2020 ; Levi Setti et al , 2020 ). A 7-year study of vitrified blastocyst transfers found that the risk of early pregnancy loss was higher using AC compared to NC or modified NC with ovulation triggering ( Levi Setti et al , 2020 ). Similarly, a retrospective study of 1846 normally ovulating patients also reported that the early pregnancy loss rate was significantly higher with AC than with NC ( Liu et al , 2020 ).…”
Section: Introductionmentioning
confidence: 94%
“…Previous studies have reported that the early pregnancy loss rate in FET was higher when using the AC protocol compared to NC or SC ( Veleva et al , 2008 ; Tomás et al , 2012 ; Cerrillo et al , 2017 ; Peigné et al , 2019 ; Liu et al , 2020 ; Levi Setti et al , 2020 ). A 7-year study of vitrified blastocyst transfers found that the risk of early pregnancy loss was higher using AC compared to NC or modified NC with ovulation triggering ( Levi Setti et al , 2020 ). Similarly, a retrospective study of 1846 normally ovulating patients also reported that the early pregnancy loss rate was significantly higher with AC than with NC ( Liu et al , 2020 ).…”
Section: Introductionmentioning
confidence: 94%
“…After screening by title and abstract, we reviewed 20 full-text and included an additional 4 articles from the reference lists of included articles and previous systematic reviews. We included nine studies in our final quantitative analysis 10 16 20–26. Two of which were RCTs22 23 both of which studied small sample sizes.…”
Section: Resultsmentioning
confidence: 99%
“…Although many studies have investigated endometrial preparation protocols and pregnancy and live birth rates 27 29 , only a limited number of studies with conflicting results have investigated endometrial preparation protocols and the risk of EP 12 , 18 , 19 . Importantly, these studies did not specifically investigate endometrial preparation protocols and targeted other factors.…”
Section: Discussionmentioning
confidence: 99%
“…However, another Chinese study investigating the association between body mass index and EP using retrospective data (n = 16,378 pregnancies) demonstrated no significant associations between endometrial preparation protocols and the risk of EP for frozen cycles 18 . Furthermore, a retrospective analysis of clinical pregnancies in Italy following single blastocyst ETs with different endometrial preparation protocols demonstrated a significantly higher EP rate for natural cycles (6/561, 3.28%) than HRC (4/585, 1.83%) and modified natural cycles (3/1749, 0.4%) 19 . Our study, using the largest sample of subjects with single frozen-thawed ET cycles demonstrated that the risk of EP did not differ for HRC compared with natural cycles.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation