Setting positive end-expiratory pressure: role in diaphragm-protective ventilation
Myrte Wennen,
Wout Claassen,
Leo Heunks
Abstract:Purpose of review
With mechanical ventilation, positive end-expiratory pressure (PEEP) is applied to improve oxygenation and lung homogeneity. However, PEEP setting has been hypothesized to contribute to critical illness associated diaphragm dysfunction via several mechanisms. Here, we discuss the impact of PEEP on diaphragm function, activity and geometry.
Recent findings
PEEP affects diaphragm geometry: it induces a caudal movement of the diaphragm do… Show more
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