Setting expectations for transcatheter mitral valve replacement in the real world

Sorajja, Paul; Cavalcante, João L.; Bapat, Vinayak

doi:10.1002/ejhf.2506

Cited by 1 publication

(2 citation statements)

References 5 publications

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“…Despite high technical success rates, concerningly 30‐day to 1‐year mortality and HFH remain higher in TMVR than TEER cohorts. This trend is, as yet, not fully understood or explained 46,67 . Of the 229 patients who underwent TMVR in the CHOICE‐MI registry, all‐cause mortality and HFH was significantly higher in those who underwent TMVR than in patients who underwent bail‐out TEER (39.2% vs. 28.8%; p > 0.05) 11 .…”

Section: Morbidity Mortality and Rehospitalization For Heart Failure ...mentioning

confidence: 99%

“…This trend is, as yet, not fully understood or explained. 46,67 Of the 229 patients who underwent TMVR in the CHOICE-MI registry, all-cause mortality and HFH was significantly higher in those who underwent TMVR than in patients who underwent bail-out TEER (39.2% vs. 28.8%; p > 0.05). 11 In the expanded clinical study, no intra-procedural deaths occurred, however six patients died prior to hospital discharge, 17 (18%) within 90 days post intervention, resulting in a total of 26 deaths by 1 year.…”

Section: Mortality and Rehospitalization For Heart Failurementioning

confidence: 99%

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Peri‐procedural management of transcatheter mitral valve replacement in patients with heart failure

Hungerford

Dahle

Duncan

et al. 2022

European J of Heart Fail

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Over the past decade, transcatheter mitral valve replacement (TMVR) technologies have evolved with the objective of improving outcomes for patients with severe mitral regurgitation (MR) deemed unsuitable for conventional mitral valve surgery. Although the safety and efficacy of transcatheter edge‐to‐edge mitral valve repair (TEER) is well‐established, there is a sense amongst innovators that a major advantage of TMVR may be to offer a more complete solution for the correction of MR in patients whose complex anatomy means that the likelihood of achieving grade 0 or 1 MR with TEER is low. However, abrupt correction of MR in a poorly prepared left ventricle poses a number of unique haemodynamic challenges, particularly when sudden elimination of regurgitant flow causes a relative increase in left ventricular (LV) afterload. Rapid reduction in LV cavity size following MR elimination may itself result in relative LV outflow tract obstruction (LVOTO), irrespective of the intrinsic risk of LVOTO associated with TMVR. Nevertheless, TMVR on a beating heart affords the opportunity to study real‐time invasive cardiac indices in high‐risk patients with acute reversal of severe MR.

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Section: Morbidity Mortality and Rehospitalization For Heart Failure ...mentioning

confidence: 99%

Section: Mortality and Rehospitalization For Heart Failurementioning

confidence: 99%

Peri‐procedural management of transcatheter mitral valve replacement in patients with heart failure

Hungerford

Dahle

Duncan

et al. 2022

European J of Heart Fail

View full text Add to dashboard Cite

show abstract

Setting expectations for transcatheter mitral valve replacement in the real world

Cited by 1 publication

References 5 publications

Peri‐procedural management of transcatheter mitral valve replacement in patients with heart failure

Peri‐procedural management of transcatheter mitral valve replacement in patients with heart failure

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