2019
DOI: 10.1177/1934578x19860014
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Setosphaerine A: A New Chlorinated Polyketide Isolated From the Entomogenous Fungus Setosphaeria rostrata

Abstract: A new chlorinated polyketide setosphaerine A (1), together with 3 known ones penicipyran D (2), 7- O-demethymonocerin (3), and monocerin (4), was isolated from the entomogenous fungus Setosphaeria rostrata. The structure of compound 1 was established on the basis of 1D/2D Nuclear Magnetic Resonance (NMR) spectroscopic and High Resolution Electro Spray Ionization Mass Spectra (HR-ESI-MS) data. Compounds 1 to 4 showed moderate cytotoxicity against 3 human tumor cell lines MCF-7, MGC-803, and Hela with IC50 value… Show more

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“…The toxin was found in another phytopathogenic fungus, Macrophomina phaseolina , which also produces other entomotoxic compounds such as mellein, cordycepin, and kojic acid [ 179 ]. Recently, monocerin was isolated from the culture of the entomogenous fungus, Setosphaeria rostrata [ 180 ].…”
Section: Low-molecular-weight Non-volatile Compoundsmentioning
confidence: 99%
“…The toxin was found in another phytopathogenic fungus, Macrophomina phaseolina , which also produces other entomotoxic compounds such as mellein, cordycepin, and kojic acid [ 179 ]. Recently, monocerin was isolated from the culture of the entomogenous fungus, Setosphaeria rostrata [ 180 ].…”
Section: Low-molecular-weight Non-volatile Compoundsmentioning
confidence: 99%