Session 3: Biofabrication

Abstract

Most powerful technique for biofabrication -3D printing still has limitations, which substantially restrict its broader use. These are inability to achieve sufficient resolution and high-density cell printing, difficulty of fabrication of multicomponent and hollow structures, difficulty of orienting of cells and limited oxygen diffusion. We advanced design of biomaterials by developing 4D biofabrication approach using special polymers, which are able to change their shape -shape-morphing polymers. We demonstrate application of 4D biofabrication approach for controlled encapsulation of cells, design of porous scaffolds with controlled porosity and pore orientation, complex 3D cell patterning as well as fabrication of hydrogel-cell hollow structures.