Sesquiterpenoids from Pallenis spinosa

Composition, Antioxidant, and Cytotoxic Activities of the Essential Oils from Fresh and Air‐Dried Aerial Parts of Pallenis spinosa

“…Several earlier studies have focused on the metabolic products of P. spinosa for taxonomic and potential medicinal applications. It has been reported that the plant is rich in sesquiterpenes and oxygenated sesquiterpenoids . Chemical analysis of the volatile oil extracted from fresh flower heads of the plant identified high percentages of oxygenated sesquiterpenoids, such as germacra‐1(10),5‐diene‐3,4‐diol, α ‐cadinol, 3‐acetoxygermacra‐1(10),5‐dien‐4‐ol, T‐cadinol, and δ ‐cadinene .…”

New Germacrane Sesquiterpenes from Salvia chinensis

“…The closest known analogues have been observed from natural sources. [11][12][13][14][15][16][17] These precedents also show the 10-membered carbocycle of the germacrane skeleton, but with different arrangements in functionality. Substances 1 and 2, on the other hand, are highly acylated members with oxy-isovaleryl groups being the most unusual ones.…”

Composition of the essential oil of Pallenis spinosa (L.) Cass. (Asteraceae)

“…This finding agrees with data previously reported for extracts obtained from the aerial parts of the plant. 5,8 The most abundant components of this fraction are the characteristic germacra-1(10),5-dien-3,4-diol (18.4%) and 3-acetoxygermacra-1(10),5-dien-4-ol (13.0%). Data of the MS spectra for these components are identical to those previously reported, 6 isolated from the chloroform extract of the plant.…”

“…and Buphtalmum spinosum L. 4 The plant is a rich source of sesquiterpenes and oxygenated sesquiterpenes; in fact, the plant material collected in Sardinia (Italy), Spain and Egypt contained, as major constituents, germacrene D, germacrene A-type epoxides and oplopanones, respectively. 5 3-β-acetoxygermacra-1(10),5-dien-4-ol was detected in a chloroform extract of the plant, 6 while two eudesmane derivatives and one oplopenone derivative were reported in a MeOH:Et 2 O:petrol ether (1:1:1) extract. 7 The extraction of the aerial parts with hexane:Et 2 O:petrol ether (1:1:1) afforded α-cadinol, shiromool and a new diepoxygermacranol.…”