Sesquiterpenoids and flavonoids from Flourensia oolepis

Guerreiro, Eduardo; Kavka, J.; Giordano, Óscar S.; Gros, Eduardo G.

doi:10.1016/0031-9422(79)80148-x

Cited by 39 publications

(27 citation statements)

References 3 publications

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“…(n=10), in good agreement with those determined by the gravimetric standard method (64.2 • 4.6 mg/g dry weight, n=10) (Guerreiro et al, 1971;Rodriguez, 1984). The coefficient of variation was 4.4~.…”

Section: Resultssupporting

confidence: 72%

High performance liquid chromatographic determination of glycoalkaloids in callus and fruits ofSolanum eleagnifolium

et al. 1989

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Section: Resultssupporting

confidence: 72%

High performance liquid chromatographic determination of glycoalkaloids in callus and fruits ofSolanum eleagnifolium

et al. 1989

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“…Previous studies on this species proved the presence of some saponins (diosgenin and 3-deoxy-D 3 -diosgenin) as well (Guerreiro et al, 1971). Diosgenin is known by its molluscicidal activity against Biomphalaria pfeifferei (Chen & Snyder, 1989).…”

Section: After 24 H Of Actionmentioning

confidence: 89%

“…No reports have indicated its use in traditional medicine, but it has been implicated in reduced weight gains, lowered animal production, teratogenic effects (Keeler et al, 1990), and neurological disorders in ruminants (Porter et al, 2003). Solanum elaeagnifolium has several interesting secondary metabolites produced by this species; the main publications have dealt with alkaloids and saponins (Feki et al, 2013;Guerreiro et al, 1971;Hanna et al, 1996a). Besides, the presence of flavonoids (Chiale et al, 1991;Hawas et al, 2013) and other phenolic compounds from leaves (Elabbar et al, 2014) was also reported.…”

Section: Introductionmentioning

confidence: 99%

Molluscicidal activity ofSolanum elaeagnifoliumseeds againstGalba truncatulaintermediate host ofFasciola hepatica: Identification ofβ-solamarine

Njeh

Feki

Koubaa

et al. 2015

Pharmaceutical Biology

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Context: The persistence of fascioliasis in many developing countries urges the search for simple, cheap, and effective substances. In this view, plants provide interesting molluscicidal activities thanks to the secondary metabolites they produce. The genus Solanum is known for its potent effect on vector snails. Materials and methods: Solanum elaeagnifolium seeds were powdered and successively extracted using n-hexane, methylene chloride, acetone, and methanol, for 20 h each. After filtration, solvents were evaporated. An acid-base treatment was conducted on seed methanolic extract to isolate total alkaloids and b-solamarine. Total saponins fraction was obtained after successive macerations and evaporations. The molluscicidal activity was evaluated by subjecting snails, in groups of 10, for 48 h to 500 mL of extracts, fractions, and pure product aqueous solutions, each containing amounts, ranging from 1 to 50 mg of plant material in 5 mg increments. Results: The methanolic extract of seeds, b-solamarine isolated for the first time from this plant and total saponins fraction showed very potent activities on snails, giving respective median lethal concentrations (LC 50 ) of 1.18, 0.49, and 0.94 mg/L. Total alkaloids fraction obtained from the methanolic extract was less active giving an LC 50 value of 14.67 mg/L. Discussion and conclusion: This study emphasizes that glycoalkaloids and saponins of Solanum elaeagnifolium are potent molluscicidal agents. Seed methanolic extract, b-solamarine, and total saponins fraction may be used as molluscicides.

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“…Ilicic alcohol [1], an eudesmane sesquiterpene, isolated from Fluorensia oolepis [2] was oxidised with Jones' reagent, by the usual method proposed for allylic alcohols [3]. Through this reaction it was possible to obtain ilicic aldehyde [2].…”

Section: Oxidationmentioning

confidence: 99%