Sesquiterpene lactones from Artemisia inculta

Marco, J. Alberto; Sanz‐Cervera, Juan F.; García-Lliso, Vicente; Guara, Miguel; Vallés-Xirau, Joan

doi:10.1016/s0031-9422(97)00020-4

Cited by 13 publications

(15 citation statements)

References 16 publications

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“…Hydroperoxide (36) was isolated as an unstable oil from Artemisia herba-alba subsp. herba-alba and Ursinia tenuifolia [71], and Artemisia barrelieri [72,73]. Peroxide (37) was isolated from the aerial parts of Chrysanthemum lavandulifolium [74], and germacranolide (38) was detected in the leaves of Artemisia ludoviciana [75].…”

Section: Sesquiterpenoid Hydroperoxidesmentioning

confidence: 99%

Phytomedicinal aspects of sesquiterpenoid peroxides: Origin, structures and biological activity

Siddiq¹,

Yaremenko²,

Ao³

et al. 2019

Frontiers Drug Chemistry Clinical Res

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Sesquiterpenoid peroxides are a rare group of natural metabolites isolated predominantly from various parts of plants. The biological activity of sesquiterpene peroxides has hardly been studied. This review provides information on the biological activity of 80 natural sesquiterpene peroxides. All isolated chemical compounds are divided into two groups. The first group includes sesquiterpene hydroperoxides and the second group includes sesquiterpene lactone endoperoxides. To determine the biological activity of sesquiterpene peroxides, we used the computer PASS program, which contains more than 1,000,000 natural and synthetic chemicals that exhibit more than 10,000 different activities. As shown by the analysis of these compounds, sesquiterpene peroxides are inhibitors of cell adhesion and also demonstrate antiulcer activity. In addition, individual representatives of sesquiterpene hydroperoxides showed antineoplastic and antimetastatic activity. On the other hand, sesquiterpene lactone endoperoxides demonstrated anti-inflammatory and antiprotozoal properties. The new data presented showed that sesquiterpene peroxides are an interesting group of natural medicinal preparations that can be used in pharmacology, medicine and related fields.

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Section: Sesquiterpenoid Hydroperoxidesmentioning

confidence: 99%

Phytomedicinal aspects of sesquiterpenoid peroxides: Origin, structures and biological activity

Siddiq¹,

Yaremenko²,

Ao³

et al. 2019

Frontiers Drug Chemistry Clinical Res

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“…(6S*,7S*,10R*)-6,10-Dimethyl-7,10-epoxyocta-11-enoic acid (4) has been isolated from the leaves of Tanacetum vulgare and it has been hypothesized to be derived from davanone by loss of a five carbon atoms chain [19]. It has been found also in A. inculta [23], A. herba-alba [27], A. lobelii ssp. canescens and A. lobelii ssp.…”

Section: Albamentioning

confidence: 99%

“…Hydroxydavanone (3) has been previously isolated from the aerial parts of Tanacetum vulgare [19], T. millefolium and T. achilleifolium [20], from the roots of Pyrethrum santolinoides [21] and from the aerial parts of several species of Artemisia: A. maritima L. [22], A. inculta [23], A. pallens [24,25], A. laciniata [26], A. herba-alba, A. reptans [27], A. lobelii. ssp.…”

mentioning

confidence: 99%

Metabolites from the Aerial Parts of the Sicilian Population of Artemisia alba

Maggio

Rosselli

Brancazio

et al. 2013

Natural Product Communications

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Phytochemical investigation of the CH 2 Cl 2 extract of the aerial parts of Artemisia alba Turra afforded one new irregular sesquiterpenoid, artemiric acid, and five known metabolites: hydroxydavanone, the coumarins isofraxidin and scopoletin, (6S*,7S*,10R*)-6,10-dimethyl-7,10-epoxyocta-11-enoic acid and artalbic acid. From the MeOH extract three flavonoids were identified: chrysoeriol, quercetin and isorhamnetin. The possible biogenetic pathways of artemiric and artalbic acids are discussed.

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“…90 The norsesquiterpene 125 has been found in an extract of the aerial parts of Artemisia inculta, collected in three different locations in Egypt. 91 The sesquiterpenes 126 and 127 have been obtained from Athanasia pinnata. 92 The aerial part of Calea crocinervosa contains the trisnorsesquiterpene lactone crocinervolide 128.…”

Section: Trisfuranosesquiterpenoidsmentioning

confidence: 99%