Serum vaspin levels and vaspin mRNA expression in subcutaneous adipose tissue in women with gestational diabetes mellitus

Comparison of serum vaspin levels and vaspin expression in adipose tissue and smooth muscle tissue in pregnant women with and without gestational diabetes

“…Similar results were observed by Jia X et al . and Mm et al., but not in other studies . The diversity of the results may be related to different ethnicity, age, gestational weeks and GDM severity .…”

“…Vaspin expression has been found in human adipose tissue as well as stomach, 18 liver, pancreas, 19 placenta 12,20 and muscle tissue. 21 While the specific tissues secreting the most vaspin remain unknown, Mm et al 13 found that the expression of vaspin mRNA and protein in SAT was higher in pregnant women with GDM than in a control group.…”

“…reported the expression of vaspin in the placenta in GDM women, but no difference was shown between the GDM and control groups. Mm et al . further explored the contribution of vaspin expression in subcutaneous adipose tissue (SAT) and found that the expression of vaspin in SAT was higher in pregnant women with GDM than in pregnant women with normal glucose tolerance.…”

“…[9][10][11][12] Huo et al 12 reported the expression of vaspin in the placenta in GDM women, but no difference was shown between the GDM and control groups. Mm et al 13 further explored the contribution of vaspin expression in subcutaneous adipose tissue (SAT) and found that the expression of vaspin in SAT was higher in pregnant women with GDM than in pregnant women with normal glucose tolerance. However, previous research has focused on the expression of vaspin in a single tissue type and has not investigated VAT, which might be more important in secreting vaspin 7 and participating in the pathogenesis of insulin resistance.…”

Dyslipidemia interaction with inflammation and insulin resistance in subjects with different body weight

“…Одними з таких є адипокін васпін [18][19][20][21] та секреторний білок, який експресується вісцеральною жировою тканиною, ОРИГІНАЛЬНЕ ДОСЛІДЖЕННЯ компенсаторна молекула щодо розвитку серцево-судинної патології -оментин [21,22]. В Україні проводились поодинокі дослідження властивостей цих пептидів, але повідомлень про дослідження їх взаємозв'язків із вмістом жирової тканини, рівнем ВЖК та лептину не знайдено.…”