2012
DOI: 10.1038/pr.2012.47
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Serum uric acid in US adolescents: distribution and relationship to demographic characteristics and cardiovascular risk factors

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Cited by 26 publications
(18 citation statements)
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“…According to the NHANES 2005-2008, the mean UA levels and the 95th percentile were 5.80 and 8.10 mg/dL, respectively, in white male adolescents and 4.50 and 6.10 mg/dL, respectively, in white female adolescents. 20) In a previously conducted Chinese study, the median UA levels were 5.8 and 4.3 mg/dL in male and female adolescents, respectively. 21) In our study, differences in UA levels based on sex were observed among the subjects.…”
Section: Discussionmentioning
confidence: 92%
“…According to the NHANES 2005-2008, the mean UA levels and the 95th percentile were 5.80 and 8.10 mg/dL, respectively, in white male adolescents and 4.50 and 6.10 mg/dL, respectively, in white female adolescents. 20) In a previously conducted Chinese study, the median UA levels were 5.8 and 4.3 mg/dL in male and female adolescents, respectively. 21) In our study, differences in UA levels based on sex were observed among the subjects.…”
Section: Discussionmentioning
confidence: 92%
“…The higher uric acid and bilirubin concentrations in adults could be explained as a protective response to increased phagocytosis of senescent erythrocytes and the higher ROS generation [ 77 , 78 ] compared with children. Additionally, the higher uric acid in adults in the present study could also be due to increased intake of purine-rich foods [ 77 , 79 , 80 ], older age, higher BMI, greater height, and greater weight compared to children [ 79 ]. The differences in antioxidant status between adults and children of the present study were apparent at rest, but also during the recovery period after eccentric exercise.…”
Section: Discussionmentioning
confidence: 99%
“…Children were categorized as having elevated or normal serum UA based on age-sex-race 95 th percentile norms [18, 19]. All routine clinical tests, except for plasma renin activity and serum aldosterone, were performed in the Johns Hopkins Hospital clinical laboratory.…”
Section: Methodsmentioning
confidence: 99%
“… SD indicates standard deviation; IQR, interquartile range; UA, uric acid; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; BPi, blood pressure index = (BP/95 th percentile BP or 140/90 if ≥ 18 yrs); HDL, high density lipoprotein cholesterol; ACEi, angiotensin converting enzyme inhibitor; ARB, angiotensin II receptor blocker; hsCRP, high sensitivity C-reactive protein; LVM, left ventricular mass; LVMI, left ventricular mass index = LVM/ht(m 2.7 ); LVH, left ventricular hypertrophy = LVMI≥95 th percentile a Normal UA defined as a serum UA <95 th percentile for age, race and sex using Harriet Lane Handbook cutoffs for <12 years [18]; NHANES for 12-19 years [19]. Elevated UA is defined as ≥95th percentile.…”
Section: Figurementioning
confidence: 99%
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