Serum Uric Acid Concentration in Overweight and Obese Women with Polycystic Ovary Syndrome / Nivelul acidului uric la femeile supraponderale și obeze cu sindromul ovarelor polichistice

Leuștean, Letiția; Dimitriu, Cristina; Fica, Simona; Ungureanu, Maria-Christina; Preda, Cristina; Mogoş, Voichiţa; Ungureanu, Didona; Vulpoi, Carmen

doi:10.1515/rrlm-2015-0010

Romanian Review of Laboratory Medicine

2015

DOI: 10.1515/rrlm-2015-0010

|View full text |Cite

Serum Uric Acid Concentration in Overweight and Obese Women with Polycystic Ovary Syndrome / Nivelul acidului uric la femeile supraponderale și obeze cu sindromul ovarelor polichistice

Letiția Leuștean¹,

Cristina Dimitriu²,

Simona Fica³

et al.

Abstract: Background: Women with polycystic ovary syndrome (PCOS)

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2020

2023

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

(2 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Obesity is linked with insulin resistance and increased risk of diabetes, hypertension, dyslipidemia, endothelial dysfunction and heart disease. 18 In this study, HbA1c and uric acid showed positive correlation with BMI and W/H ratio in PCOS women. This indicates that obesity also plays an important role in this disorder.…”

supporting

confidence: 52%

See 1 more Smart Citation

Assessment of glycated hemoglobin and uric acid level in polycystic ovarian syndrome in a Tertiary Care Institute of Marathwada region

Aghade¹,

Bavikar²

2020

IJCBR

View full text Add to dashboard Cite

Introduction: The Polycystic Ovary Syndrome (PCOS) is one of the most common reproductive endocrine disorders, affecting 5-10% of women in the reproductive age. Insulin resistance is the hallmark of this disorder. PCOS has been epidemiologically linked to an increased risk for type 2 diabetes mellitus and cardiovascular diseases. The present study was planned to study glycated hemoglobin (HbA1c) and uric acid level in patients of PCOS. Materials and Methods:The study comprised of 60 women with PCOS as cases and 60 healthy females as controls. HbA1c and uric acid level were measured in all participants. Results: Glycated hemoglobin and serum uric acid were significantly increased in PCOS group and showed positive correlation with body mass index and waist: hip ratio. The prevalence of raised HbA1c was 40% in PCOS women. Conclusion: In our study we found significant alterations in HbA1c and uric acid level in cases of PCOS. Early identification of these changes and timely intervention can reduce morbidity due to type 2 diabetes mellitus and cardiovascular diseases in PCOS. This will help to redefine the paradigms of PCOS care in India.

show abstract

supporting

confidence: 52%

“…17 Studies have shown that, decrement in serum uric acid concentration of high-risk patients improved the endothelial function and resulted in reduced cardiovascular morbidity and mortality. 18 As PCOS women have 50% increased risk for cardiovascular complications, serum uric acid can be used for early detection of high risk patients.…”

mentioning

confidence: 99%

Assessment of glycated hemoglobin and uric acid level in polycystic ovarian syndrome in a Tertiary Care Institute of Marathwada region

Aghade¹,

Bavikar²

2020

IJCBR

View full text Add to dashboard Cite

show abstract

Serum Levels of Uric Acid in Females of Polycystic Ovarian Syndrome with and without Insulin Resistance

Riaz¹,

Ibrar

Fatima

et al. 2023

PJHS

View full text Add to dashboard Cite

Females suffering from polycystic ovarian syndrome have marked insulin resistance, independent of obesity. These women also have multiple risk factors for cardiovascular diseases, such as dyslipidemia, insulin resistance and hypertension. Uric acid level has also been recognized recently as a risk factor for cardiovascular diseases, females with PCOS may have abnormal profile of uric acid. Objectives: To compare uric acid levels in females of polycystic ovarian syndrome with and without insulin resistance. Methods: Cross-sectional comparative study was conducted in Biochemistry Department of Islam Medical College, Sialkot. Patients were divided into 2 groups based on their insulin resistance. In group-A patients were taken with PCOS and in group-B patients were taken with PCOS without insulin resistance. A total of 108 cases (54 in each group) fulfilling the inclusion/exclusion criteria. In both groups uric acid level was measured by standard procedure. Data were entered and analyzed using SPSS version 22 accordingly. Results: The mean age for all the cases was 29.43 ± 4.08 years, while mean age in insulin resistance group was 29.33 ± 4.06 years and mean age in non-insulin resistance group was 29.52 ± 4.13 years. The mean uric acid in insulin resistance and non-insulin resistance group was 4.92 ± 0.89 mg/dl and 4.48 ± 0.95 mg/dl with significantly higher mean uric acid in insulin resistance group, p-value < 0.05. Conclusion: We conclude that females having PCOS with insulin resistance had higher mean uric acid levels. Females with insulin resistance must be prevented from hyperuricemia to minimize the further risk of insulin resistance.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Serum Uric Acid Concentration in Overweight and Obese Women with Polycystic Ovary Syndrome / Nivelul acidului uric la femeile supraponderale și obeze cu sindromul ovarelor polichistice

Abstract: Background: Women with polycystic ovary syndrome (PCOS)

Cited by 2 publications

References 40 publications

Assessment of glycated hemoglobin and uric acid level in polycystic ovarian syndrome in a Tertiary Care Institute of Marathwada region

Assessment of glycated hemoglobin and uric acid level in polycystic ovarian syndrome in a Tertiary Care Institute of Marathwada region

Serum Levels of Uric Acid in Females of Polycystic Ovarian Syndrome with and without Insulin Resistance

Contact Info

Product

Resources

About