Serum uric acid and lipid profile in diabetic retinopathy in rural Haryana, India

Sethi, Sumita; Reddy, Varikasuvu Seshadri; Lamba, Sonika

doi:10.18203/2349-3933.ijam20161081

Cited by 5 publications

(5 citation statements)

References 9 publications

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“…In studies on Indian population, Gnaneswaran et al7 found significantly higher values of serum TC and LDL-C levels in DR patients, whereas, Rema et al11 reported significantly higher mean serum TC, TG and non- HDL-C concentrations in subjects with DR. In studies comparing patients with DR and age matched healthy non diabetic controls, Kiran et al2 reported significantly deranged lipid profile in DR patients, while Agarwal et al20 found a statistically significant lower value of mean HDL-C in diabetic patients with or without DR. Rimpal P et al found serum TG, LDL-C and TC were elevated and serum HDL-C was decreased in diabetic subjects as compared to healthy control, whereas serum TG, TC and LDL –C were more elevated in those with retinopathy than that those without retinopathy 21…”

Section: Discussionmentioning

confidence: 98%

Comparison of serum lipid profile in Type-2 Diabetics withand without retinopathy in Pakistani population

Amin¹,

Islam²,

Mehboob³

2016

Pak J Med Sci

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Objective:To compare serum cholesterol, TG, HDL-C and LDL-C concentrations between type-2 Diabetes mellitus (DM) patients with retinopathy and without retinopathy and to study association between various modifiable risk factors of Diabetic retinopathy (DR).Methods:The study included 300 patients with type 2 DM; 140 of them were without DR (Group-I) and 160 were with DR (Group-II). Serum total cholesterol, LDL-C, HDL-C, and TG levels were determined. SPSS 17.0 for windows was used for statistical analysisResults:Overall, mean age of study population was 48.86 ± 5.62 years. Subjects with DR were older (P < 0.018), had higher fasting plasma glucose (P < 0.01) and higher HbA1c (P <0.01) concentrations compared with those without DR. Analysis of serum cholesterol, LDL-C, HDL-C and TG among subgroups of patients with no DR, with NPDR and PDR showed statistically significant difference (p <0.01). There was strong positive correlation of severity of DR with BSF, HbA1c, serum LDL-C, total cholesterol and TG.Conclusion:The serum cholesterol, TG, HDL-C and LDL-C concentrations were found to be significantly deranged in patients with DR as compared to those without DR.

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Section: Discussionmentioning

confidence: 98%

Comparison of serum lipid profile in Type-2 Diabetics withand without retinopathy in Pakistani population

Amin¹,

Islam²,

Mehboob³

2016

Pak J Med Sci

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“…DR as expected was related to poorer glycemic control and lipid profile as well as worsening renal function ( 38 – 40 ). Dyslipidemia has been reported to be associated with CVD and DR ( 41 ) and indeed CVD was also related to DR.…”

Section: Discussionmentioning

confidence: 99%

Clinical and Biochemical Associations with Diabetic Retinopathy in Male Patients in the Gaza Strip

AbuMustafa

2017

Front. Endocrinol.

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BackgroundThere are limited data on the prevalence and risk factors for diabetic retinopathy (DR) in the Gaza Strip.ObjectiveTo assesses clinical and biochemical associated with DR in males with type 2 diabetes mellitus (T2DM) in the Gaza Strip.MethodsOne hundred and fifty males with T2DM from the Gaza Strip underwent a questionnaire interview, serum biochemical analysis, and assessment of their previous urine and blood results.ResultsThe prevalence of DR was 24.7%. The duration of diabetes and prevalence of neuropathy, nephropathy, cardiovascular disease, and recurrent infections were significantly higher among patients with DR compared with those without DR (p < 0.05). Serum urea, creatinine, glucose, cholesterol, and low-density lipoprotein cholesterol were significantly elevated, whilst eGFR and high-density lipoprotein cholesterol were significantly lower in patients with DR compared with patients without DR (p < 0.05). Urinary albumin concentration and albumin creatinine ratio (ACR) was higher in patients with DR. ACR correlated significantly with the duration of T2DM (r = 0.311, p < 0.001), glucose (r = 0.479, p < 0.001), urea (r = 0.337, p < 0.001), creatinine (r = 0.275, p = 0.001), and GFR (r = −0.275, p < 0.001).ConclusionThese data show a high prevalence of DR in an unselected cohort of patients with T2DM and relationships to modifiable risk factors in Gaza.

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“…Mean HbA1c and mean FBS significantly correlated with UA ( P = 0.01 and P = 0.02, respectively) in both groups. A deranged HDL profile and a significant correlation between glycemic control and HbA1c and UA were thus found in two study groups compared to the healthy control group [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of levels of uric acid and lipid profile in hospitalized patients with diabetes

et al. 2023

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Objective Diabetes is the most common metabolic disorder that leads to various complications, and among these complications, disruption in the lipid profile and serum uric acid (SUA) is one of the significant cases that can lead to the deterioration of the health status of patients with diabetes. So, we aimed to evaluate the level of SUA and lipid profiles in patients with diabetes. A total of 230 patients with diabetes who were admitted to Razi Hospital, Rasht, Iran, were enrolled in this study. Demographical data and clinical characteristics of the patients include gender, body mass index (BMI), duration of diabetes, history of smoking, FBS, HbA1c, SUA, Creatinine (Cr), Cholesterol (Chol), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TG), retinopathy, hypertension, ischemic heart disease (IHD), and microalbuminuria were recorded. All data were analyzed using the SPSS version 21 by a significant level < 0.05. Result According to our results, 70 were male, and 160 were female, with a mean age of 57.36 ± 8.05 years and a mean BMI of 28.10 ± 4.62. The most frequent comorbidities were hypertension, 67%. The serum level of FBS, HBA1c, SUA, Cr, Chol, LDL, HDL, and TG were 191.47 ± 71.66 mg/dL, 7.94 ± 1.21 mg/dL, 5.65 ± 1.95 mg/dL, 0.94 ± 0.16 mg/dL, 167.28 ± 45.22 mg/dL, 95.91 ± 37.03 mg/dL, 39.78 ± 10.44 mg/dL, and 186.75 ± 76.65 mg/dL, respectively. Only UA had a significant relationship with TG level (P < 0.05).

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Serum uric acid and lipid profile in diabetic retinopathy in rural Haryana, India

Cited by 5 publications

References 9 publications

Comparison of serum lipid profile in Type-2 Diabetics withand without retinopathy in Pakistani population

Comparison of serum lipid profile in Type-2 Diabetics withand without retinopathy in Pakistani population

Clinical and Biochemical Associations with Diabetic Retinopathy in Male Patients in the Gaza Strip

Evaluation of levels of uric acid and lipid profile in hospitalized patients with diabetes

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