Serum Trace Elements and Fat-soluble Vitamins A and E in Healthy Pre-school Children from a Venezuelan Rural Community

Brunetto, Marı́a del Rosario; Alarcon, O. M.; Davila, Evelyn P.; Contreras, Yaritza; Gallignani, Máximo; Rondón, Carlos; Burguera, J.L.; Burguera, M.; Angarita, Coromoto

doi:10.1016/s0946-672x(99)80022-4

Cited by 7 publications

(6 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A significant association of Zn with vit A has been described in multiple other populations (24,25) and is confirmed in this study despite the treatment with high doses of vit A. Zn is required for hepatic synthesis of RBP, implying a regulatory role for Zn in mobilizing vit A within cells and from the liver (26). As observed by others (27), there was however no association of serum Zn and RBP in this CF population.…”

Section: Discussionsupporting

confidence: 85%

Serum Zinc Concentrations in Cystic Fibrosis Patients Aged Above 4 Years: A Cross-sectional Evaluation

Biervliet

Velde

et al. 2007

Biol Trace Elem Res

View full text Add to dashboard Cite

Aim: Assess the risk of zinc (Zn) deficiency in the older cystic fibrosis (CF) population. Method:Cross sectional investigation of all CF patients above the age of 4 followed at the Ghent university centre between 2002 and 2003. Data on age, weight and height z-score, pancreatic and pulmonary functions, chronic pseudomonas infection and CF transmembrane conductance regulator (CFTR) mutations were collected. Serum Zn, vitamin A, E, retinol binding protein (RBP), albumin, sedimentation rate, total IgG and cholesterol were determined. Serum Zn was compared with a local healthy control group (1) and with literature data (3). Results: 101 patients (median age 16 years) were included. There was no difference in serum Zn concentration between CF patients and controls. In CF patients no difference in serum Zn concentration between pancreatic sufficient or insufficient patients was seen. Serum Zn was not associated to nutritional status or height Z-score. A significant association serum Zn to serum albumin (p< 0.0005) and to vitamin A (p< 0.01) was seen. No associations of serum Zn to serum vitamin E, RBP, cholesterol or CFTR were present. There is a significant association serum Zn -forced vital capacity (p<0.01). Serum Zn was not associated to inflammatory parameters or chronic pseudomonas infection. Conclusion: Comparison of CF patients with local controls revealed no significant differences. However, since persisting steatorrhoea increases Zn loss (2) and 12.6% of our population has a serum Zn below the P 2.5 value of the NHANES II study (3), there could remain an increased risk of Zn deficiency in some CF patients. Further on the association with pulmonary function needs more investigation.

show abstract

Section: Discussionsupporting

confidence: 85%

Serum Zinc Concentrations in Cystic Fibrosis Patients Aged Above 4 Years: A Cross-sectional Evaluation

Biervliet

Velde

et al. 2007

Biol Trace Elem Res

View full text Add to dashboard Cite

show abstract

“…Co levels reported to be significantly higher in children with iron deficiency anaemic (189±49 µg/dl) than those of controls (163±37 µg/dl) [27]. In the rural community of Canagua, Merida State, Venezuela estimated the Cu among pre-school children aged 2-6 years to be 1.18±0.30mg/l, and the level decreased with age [10]. But in the present study, it is not same and the level of Cu is slightly higher in case of boys than girls.…”

Section: Discussionmentioning

confidence: 96%

“…Zn levels of neonates at fullterm and 6 months reported to be at 12.0±2.6 ppm and 13.8±2.5 ppm respectively [14]. The mean serum concentrations of zinc among children aged 2-6 years found to be 7.4±2.5 and the levels increase with age [10].…”

Section: Discussionmentioning

confidence: 99%

“…Trace element determination in blood serum has become important to investigate the vital role in human metabolism as well as to obtain information regarding the health status of individuals [6]. Several studies [7][8][9][10][11][12][13][14][15][16][17] were undertaken in measuring trace elements in the serum/plasma using various techniques like instrumental neutron activity analysis (INAA), flame atomic absorption spectrometry (FAAS), Electro-thermal atomic absorption spectrometry (ETAAS) and Proton Induced X-ray Emission (PIXE) in different age groups but no such studies were reported for the most vulnerable preschool children in India. The current study aims at evaluating the levels of serum trace elements among the preschool children in Odisha by PIXE method, which can quantify trace element down to parts per million (ppm) or sub-ppm levels [18].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Status of Serum Trace Elements among Preschool Children in Rural Bhubaneswar, Odisha, India

Sethy

Bulliyya

Rautray

et al. 2014

IJANHS

View full text Add to dashboard Cite

One in every three malnourished children in the world is from India leading to high child morbidity and mortality. Out of these, preschool children constitute the most vulnerable segment of any community. The present study aimed at assessing the levels of trace elements in preschool children aged 2-5 years in rural Gram Panchayats (GP) of Bhubaneswar block, Odisha, India. A cross-sectional study was undertaken covering 176 children (boys 100 and girls 76) from 8 GPs selected on random basis. Blood was collected and lyophilized serum subjected to trace elements by proton induced X-ray emission (PIXE) technique. Overall, the mean levels of manganese (Mn), cobalt (Co), nickel (Ni), copper (Cu), zinc (Zn), selenium (Se), bromine (Br) and lead (Pb) were 19.2±3.39, 0.86±0.52, 3.2±0.9, 4.04±0.87, 15.26±2.27, 1.03±0.95, 59.95±6.55 and 0.29±0.66 ppm respectively. The concentrations of Mn, Ni, Cu and Br were increased significantly with age, while levels of Co, Zn, Se, and Pb showed random variations. The mean Co, Ni, Cu, Se, Pb and Br levels were found to be higher among boys than girls however, only Cu and Br found to be significantly high. There were significant correlations observed between some of elements (Mn-Br, Co-Ni, Ni-Cu, Ni-Br, Cu-Zn and Cu-Br) and Se levels negatively associated with Pb. The mean concentrations obtained for most trace elements with an exception of Mn were within the ranges reported by earlier studies.

show abstract

“…Moreover, there are another studies to determine Fe, Zn and Cu in the thyroid cells and its effect on the antioxidant enzymes in these cells especially in the patients animals with thyroid deficiency (Brunetto et al, 1999). Also, these studies have concerned with the effect of Fe, Cu and Zn on thyroid gland cancer by determination of these elements in the blood serum of the patients with this disease (Kelson & Shamberger, 1978).…”

Section: Scientific Studies Vol -Journal Of Kirkuk Universitymentioning

confidence: 99%

Determination of some trace elements Zn,Cu and Fe in the blood serum for patients with thyroid disease in middle and south of Iraq using atomic absorption spectrophotometer.

K.Ahmad¹,

Aeyd²,

Hussein³

2007

KUJSS

View full text Add to dashboard Cite

This investigation included the determination of some trace elements Zn, Cu, and Fe in the blood serum by flame-atomic absorption spectrometry after finding the optimum conditions for the estimation which involve the wave length, spectral band, lamp current, the burner width and the burner height.The concentration of zinc in the blood serum of the patients with hyperthyroidism was in the range of (0.596-0.681mg.l-1) which was lower than that of control concentration range (0.801-0.850mg.l-1) whereas for the patients with hypothyroidism was (0.601-0.748mg.l-1).The concentration of cupper in the patients with hyperthyroidism was higher range (0.93-1.12mg.l-1) than that of average concentrations in control (0.85-0.86mg.l-1) but decreased in the patients with hypothyroidism in the range of (0.77-0.83mg.l-1).The concentration of iron in the serum was increased in the patients with hyperthyroidism (0.97-1.03mg.l-1) and in the patients with Hypothyroidism (0.80-0.91mg.l-1) comparing with control concentrations (0.90-0.95mg.l-1).The concentration linear range was (4-0.5) mg.l-1 and correlation coefficient (r) was not less than 0.984. The statistical and other analytical results show that the relative standard deviation RSD% for trace elements (Zn, Cu, Fe) were (2.4, 1.5, 2.3) and detection limits were (0.0063, 0.0087, 0.0093)mg.l-1 respectively with percent recovery ranged between (95.0-100)%. The results obtained by this research give a good explanation for the spread of thyroid disease in middle and south of Iraq.

show abstract

Serum Trace Elements and Fat-soluble Vitamins A and E in Healthy Pre-school Children from a Venezuelan Rural Community

Cited by 7 publications

References 56 publications

Serum Zinc Concentrations in Cystic Fibrosis Patients Aged Above 4 Years: A Cross-sectional Evaluation

Serum Zinc Concentrations in Cystic Fibrosis Patients Aged Above 4 Years: A Cross-sectional Evaluation

Status of Serum Trace Elements among Preschool Children in Rural Bhubaneswar, Odisha, India

Determination of some trace elements Zn,Cu and Fe in the blood serum for patients with thyroid disease in middle and south of Iraq using atomic absorption spectrophotometer.

Contact Info

Product

Resources

About