Serum Total Cholesterol Levels and Lipoprotein β/α Ratios in Normotensives and Hypertensives : A MASS SURVEY IN YAMAGUCHI PREFECTURE

Mise, Junichi; Sakaguchi, Ryuhei; Kuranari, Hiroya; Mizuta, W; Fujii, Hideo

doi:10.1253/jcj.26.606

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“…He was kept in bed thereafter until he died. He gradually became exhausted and died on November 21,1962. His blood pressure had been markedly elevated for years in association with left ventricular hypertrophy and the episode of speech disturbance was suggestive of CVD.…”

Section: Resultsmentioning

confidence: 99%

Epidemiological Studies on Cerebrovascular Diseases in Hisayama, Kyushu Island, Japan

et al. 1964

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Studies were undertaken to show an actual incidence of cerebrovascular diseases versus heart diseases in a selected community in Japan. The whole population aged over forty, which was subjected to the studies, was 1,841 at the time when they started. In this report we described the prevalence of abnormal cardiovascular findings revealed by cross-sectional study in 1,658 (90.1% of all subjects) and also some of the results obtained by follow-up study up to the present. In the latter, the most effort was directed to obtain accurate diagnosis in all death cases in this particular population. Fifty-six cases died during the period of eighteen months, among which 17 cases (30.4 per cent) underwent postmortem examinations. Death attributable to cerebrovascular diseases much exceeded to that to heart diseases, among which cerebral hemorrhage was more predominant to cerebral infarction.T is generally assumed that in western countries the incidence of death attributable to heart diseases (HD) is higher than that to cerebrovascular diseases (CVD), however, the statistical data in Japan have been shown to be quite the reverse. In 1961, Goldberg and Kurlandl) reported that the incidence of CVD in Japan was the highest among those in 33 countries and it was attributable to an exceedingly high incidence of cerebral hemorrhage compared to that of cerebral infarction. In regards with this peculiarity of CVD in Japan, they discussed the possibility of a more accurate diagnostic approach before final conclusions were reached.Most of the studies conducted not only in Japan but also in other countries are based upon hospital records or death certificate. However, hospital records may not represent an actual incidence of the disease in a given population since admissions to hospitals are selected by the nature of the disease and also by socioeconomical conditions. Furthermore, reliability of From the Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.This investigation was supported in part by grant (NB-03642-1), U. S. Public Health Service. 12Vol. 5 No. 1 EPIDEMIOLOGICAL STUDIES ON CEREBROVASCULAR DISEASES 13 death certificate in classifying diseases is not very certain unless postmortem examinations are performed, particularly in those cases which terminate in a relatively short period after the initiating diseases. The present investigation was undertaken to show an actual incidence of CVD and HD in a selected community of Japan, called Hisayama, typical of rural areas in Kyushu Island. This preliminary report deals with the cross-sectional studies as well as some of the results obtained by follow-up studies to the present time.BACKGROUND OF HISAYAMA2)

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Section: Resultsmentioning

confidence: 99%