Serum thyroid hormones and trace element concentrations in crossbred holstein cattle naturally infected with Theileria annulata

Badiei, Khalil; Mostaghni, K.; Pourjafar, Mehrdad; Ghane, Mohsen; Ebadolah, Mohammadi

doi:10.1007/s00580-010-0962-0

Cited by 11 publications

(11 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Significant changes in cattle infected with Theileria annulata were reported in several studies (3,(13)(14)(15)(16). In the present study; RBC count, PCV and Hb concentration in cattle with theileriosis were significantly lower than healthy ones (P<0.05).…”

Section: Discussion and Conclussionsupporting

confidence: 58%

Theileria annulata ile Doğal Enfekte Sığırlarda Serum Kobalt, Bakır, Demir, Kalsiyum, Fosfor ve Magnezyum Konsantrasyonlarının Değerlendirilmesi

Kozat¹

2017

Atatürk Üniversitesi Veteriner Bilimleri Dergisi

View full text Add to dashboard Cite

The purpose of this study was to evaluate serum albumin, glucose, calcium (Ca), cobalt (Co), copper (Cu), iron (Fe), magnesium (Mg), and phosphorus (P) in cows with naturally infected with Theileria annulata. The material of this study was a total of 15 cattle with different ages, breeds and genders diagnosed as theileriosis according to clinical and microscopical examination. According to statistical analyses of biochemical parameters; serum glucose, Ca, Co, Cu, Fe, Mg, and P concentrations were detected significantly low in cattle with theileriosis (P<0.001). In conclusion; mineral substance levels were altered in cattle naturally infected with Theileria annulata. Additionally to the classical treatment of theileriosis, administering mineral supplements including Ca, Co, Fe, Cu, Mg, and P to the animals is thought to be more useful in treatment.

show abstract

Section: Discussion and Conclussionsupporting

confidence: 58%

Theileria annulata ile Doğal Enfekte Sığırlarda Serum Kobalt, Bakır, Demir, Kalsiyum, Fosfor ve Magnezyum Konsantrasyonlarının Değerlendirilmesi

Kozat¹

2017

Atatürk Üniversitesi Veteriner Bilimleri Dergisi

View full text Add to dashboard Cite

show abstract

“…According to previous studies, schizont-infected cells may disseminate through the lymphoid tissues into pituitary and thyroid glands and cause injury and reduce their secretions (Forsyth et al, 1999). It has been reported that following experimental infection with T. annulata, thyroid hormones decreased significantly (Garg et al, 2001;Khalil et al, 2011). Reduced thyroid secretion rate during feed deprivation has also been reported in farm animals (Garg et al, 2001) and it has been postulated that the lower level of T 3 and T 4 could partly be due to the anorexia condition prevailing in the disease.…”

Section: Discussionmentioning

confidence: 99%

Bovine Theileriosis: Effects on the Status of Thyroid Hormones, Homocystein, Serum Lipids and Lipoproteins

Razavi¹,

Moghaddas²,

Rakhshande³

et al. 2015

Research J. of Parasitology

View full text Add to dashboard Cite

Tropical theileriosis of cattle is a common tick-borne disease in tropical and subtropical regions and is recognized as a disease of major economic importance. This study aimed to determine whether Theileria annulata infection influences the plasma homocystein (Hcy), thyroid activity and serum lipid status in infected cattle. Fifty crossbred Holstein cattle, naturally infected with Theileria annulata were selected and divided into 3 subgroups according to their parasitemia rates (<2, 2-4, 4-8%). Also, 10 non-infected cattle were assigned as controls. Blood samples were collected and hematological parameters, plasma Homocystein (Hcy), thyroid hormones (T 3 , T 4 , free T3 (fT 3 ) and free T 4 (fT 4 )) and the concentrations of serum lipid and lipoproteins (cholesterol, triglyceride and lipoproteins including HDL, LDL and VLDL cholesterol) and phosphatidylserine (PS) on erythrocytes were measured. According to the results, significant elevations were observed in the concentration of plasma Hcy (hyperhomocysteinemia) in the infected groups compared to controls. In addition, we conclude that T. annulata can interfere with the lipid metabolism, which is particularly characterized by substantial decreases in the levels of cholesterol, LDL and HDL in the serum of affected animals. In spite of remarkable influences of the parasite on Hcy and lipid contents of the serum, our study proved that tropical theileriosis did not affect the thyroid hormones during parasitemia. This study demonstrates that the infection of cattle with Theileria annulata is mainly characterized by the anemia. Also, evidenced elevation in the level of homocystein (hyperhomocysteinemia) in parasitized cattle can result in oxidative stress on erythrocytes and the probable endothelial injuries. In addition, T. annulata can induce failure in lipid metabolism which is particularly featured by a decrease in the cholesterol, LDL-cholesterol and HDL-cholesterol concentrations; however the parasite cannot implement significant influences on the thyroid hormones in the affected cattle.

show abstract

“…Some reports stated that schizont-infected cells may disseminate through the lymphoid tissues into pituitary and thyroid glands, causing injury and reducing their secretions [9]. Also, it has been reported that following experimental [21,22] and natural [23] infections with T. annulata in cattle, thyroid hormones decreased significantly. It has been postulated that the lower level of T 3 and T 4 , could partly be due to the anorexia condition, prevailing in the disease.…”

Section: Discussionmentioning

confidence: 99%

Malignant Ovine Theileriosis: Alterations in the Levels of Homocysteine, Thyroid Hormones and Serum Trace Elements

Nazifi¹

2012

J Bacteriol Parasitol

View full text Add to dashboard Cite

Introduction: Malignant ovine theileriosis is a fatal disease of sheep caused by the pathogenic species of protozoans of the genus Theileria. This study was designed to estimate the levels of plasma homocysteine (Hcy), serum thyroid hormones, the serum trace elements and to evaluate their correlations in different parasitemia rates in naturally Theileria infected sheep. Materials and Methods: 50 Iranian sheep, about 1-2 years old, naturally infected with T. lestoquardi were selected and divided into 2 subgroups according to parasitemia rates (<2%, 2-4%). 10 non-infected animals were also selected as controls. Blood samples were collected and Hcy, thyroid hormones and major trace elements were measured. Results: Significant decrease in the values of red blood cell count (RBC), packed cell volume (PCV) and hemoglobin confirmed that anaemia had occurred in the infected sheep. Significant increase in Hcy and some trace elements (Mn, Fe and Zn), significant decrease in the values of thyroxine (T 4) and free tri-iodothyronine (fT 3) were observed. Conclusion: Substantial elevations in plasma Hcy can potentially produce endothelial injuries and consequently help the formation of anaemia. On the other hand, significant decrease in T 4 and fT 3 and increase in some trace elements (Mn, Fe and Zn) besides the lack of any changes in the other related factors, indicate that the infection of sheep with lower than 4% parasitemia rates, can induce negative effects on the secretion and concentrations of thyroid hormones, but the infection could not cause reverse effects on important trace elements.

show abstract

Serum thyroid hormones and trace element concentrations in crossbred holstein cattle naturally infected with Theileria annulata

Cited by 11 publications

References 29 publications

Theileria annulata ile Doğal Enfekte Sığırlarda Serum Kobalt, Bakır, Demir, Kalsiyum, Fosfor ve Magnezyum Konsantrasyonlarının Değerlendirilmesi

Theileria annulata ile Doğal Enfekte Sığırlarda Serum Kobalt, Bakır, Demir, Kalsiyum, Fosfor ve Magnezyum Konsantrasyonlarının Değerlendirilmesi

Bovine Theileriosis: Effects on the Status of Thyroid Hormones, Homocystein, Serum Lipids and Lipoproteins

Malignant Ovine Theileriosis: Alterations in the Levels of Homocysteine, Thyroid Hormones and Serum Trace Elements

Contact Info

Product

Resources

About