Serum sulfonylurea receptor-1 is correlation to perihematomal edema after intracerebral hemorrhage and as a biomarker of clinical prognosis in patients with intracerebral hemorrhage
Abstract:Background
Sulfonylurea receptor-1(Sur1) and transient receptor potential melastatin 4(Trpm4) are implicated in acute brain injury. We determine whether serum Sur1 and Trpm4 concentrations are associated with spontaneous intracerebral hemorrhage(ICH) related perihematomal edema(PHE) and clinical outcome after ICH.
Methods
Serum Sur1 and Trpm4 concentrations were measured in 51 healthy controls and 51 patients with ICH. modified Rankin Scale (mRS) score and non-contrast computed tomography (NCCT) were recorde… Show more
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