Serum sphingolipids aid in diagnosing adult HIV-negative patients with pulmonary cryptococcosis: a clinical cohort study
Lee-Fong Yau,
Wai-Him Chan,
Yuan-Xiang Li
et al.
Abstract:Background
Pulmonary cryptococcosis (PC) contributes to the ongoing global disease burden in human immunodeficiency virus (HIV)-negative populations. Since some PC patients are misdiagnosed under existing diagnostic guidelines, new diagnostic markers are needed to improve diagnostic accuracy and therapeutic efficacy and reduce disease risk.
Methods
Our previously established sphingolipidomic approach was employed to explore the use of serum sphingolipids (SPLs) in diagn… Show more
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